Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Laser Unit, Division of Dermatology, Rabin Medical Center, Petah-Tiqva, Israel.
J Cosmet Dermatol. 2021 Aug;20(8):2515-2518. doi: 10.1111/jocd.13912. Epub 2021 Jan 1.
Non-ablative fractionated lasers for facial rejuvenation are increasingly preferred over ablative lasers due to their minimal downtime and fewer adverse events. The synergistic effect of the Q-switched fractional (QSF) 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, in combination with the non-fractional microsecond pulsed technology has yet to be fully evaluated.
Our objective was to determine the safety and efficacy of this combination treatment for skin rejuvenation.
Patients who underwent treatment using the QSF-Nd:YAG laser, followed by the non-fractional microsecond pulsed Nd:YAG were evaluated retrospectively using a novel 3D imaging modality for degree of facial erythema, wrinkles surface area, and wrinkle depth. Pain perception, adverse effects, and patient satisfaction were assessed at the 2-month post-treatment follow-up visit, graded on a scale of 1- 5 (1 = not satisfied, 5 = very satisfied).
Ten female patients' ages 44-67 (mean 55 years) completed both treatment and follow-up period, with an overall mild improvement in facial erythema and wrinkle surface area (mean improvement of 18% and 19.5% accordingly), as well as a mild improvement in overall wrinkle depth. Pain and adverse effects were mild and transient. Patients' satisfaction was high.
The combination of the QSF-Nd:YAG laser and non-fractional microsecond pulsed technology, using a single Nd:YAG 1064 nm laser platform, was found safe and effective as a non-ablative modality for facial rejuvenation, as demonstrated by a novel 3D imaging modality.
由于非剥脱性分段式激光治疗的恢复期极短,不良反应较少,因此,其在面部年轻化中的应用日益受到青睐,已逐渐取代剥脱性激光。Q 开关分段式(QSF)1064nm 掺钕钇铝石榴石(Nd:YAG)激光与非分段式微秒脉冲技术联合应用的协同效应尚未得到充分评估。
本研究旨在评估联合应用 QSF-Nd:YAG 激光与非分段式微秒脉冲 Nd:YAG 激光治疗的安全性和有效性。
回顾性分析了 10 例接受 QSF-Nd:YAG 激光治疗后,再行非分段式微秒脉冲 Nd:YAG 激光治疗的患者,采用新型 3D 成像技术评估其面部红斑程度、皱纹表面积和皱纹深度的改善情况。在治疗后 2 个月的随访中,采用 1-5 分制评估患者的疼痛感知、不良反应和满意度(1 分表示不满意,5 分表示非常满意)。
10 例年龄为 44-67 岁(平均 55 岁)的女性患者完成了治疗和随访,其面部红斑和皱纹表面积均得到整体轻度改善(分别改善 18%和 19.5%),整体皱纹深度也得到轻度改善。疼痛和不良反应轻微且短暂。患者满意度高。
新型 3D 成像技术证实,采用单一 Nd:YAG1064nm 激光平台联合应用 QSF-Nd:YAG 激光与非分段式微秒脉冲技术,作为一种非剥脱性治疗方式,用于面部年轻化是安全有效的。