The USFetus Research Consortium, Miami, FL, USA.
Applied Basic Sciences, Houston, TX, USA.
J Matern Fetal Neonatal Med. 2022 Nov;35(21):4142-4148. doi: 10.1080/14767058.2020.1847076. Epub 2020 Dec 25.
We have previously described a gestational age-independent sonographic parameter to assess fetal lung growth in the right lung (right quantitative lung index, or QLI-R). The purpose of this study was to develop a similar sonographic parameter to assess the growth of the left lung in the fetus, independent of gestational age, or QLI-L.
A new index, the QLI-L was derived using published formulas for the head circumference (HC) and the area of the base of the left lung (LA), with the corresponding percentiles.
Left lung growth can be expressed using the following formula: The 50th percentile of the QLI-L remained approximately constant at 1.0 for the GA between 16-32 weeks. A small left lung (<1st percentile) was defined as a QLI-L < 0.5.
Fetal left lung growth can be adequately described independent of gestational age using the QLI-L. Further experience is needed to assess the clinical accuracy of the QLI-L in characterizing fetal left lung growth.
我们之前描述了一种与胎龄无关的超声参数，用于评估右肺的胎儿肺生长（右定量肺指数，或 QLI-R）。本研究的目的是开发一种类似的超声参数，用于评估胎儿左肺的生长，与胎龄无关，即 QLI-L。
使用已发表的头围（HC）和左肺基底面积（LA）公式，推导出新的指数 QLI-L，并给出相应的百分位数。
左肺生长可以用以下公式表示：QLI-L 的第 50 百分位数在 16-32 周的 GA 之间基本保持在 1.0 不变。小左肺（<第 1 百分位）定义为 QLI-L<0.5。
使用 QLI-L 可以充分描述与胎龄无关的胎儿左肺生长。需要进一步的经验来评估 QLI-L 在描述胎儿左肺生长方面的临床准确性。
