Johns Hopkins University School of Nursing, Baltimore, MD, USA.
Int J Artif Organs. 2021 Aug;44(8):574-579. doi: 10.1177/0391398820982622. Epub 2020 Dec 25.
Poor sleep quality and depression remain understudied in patients implanted with a left-ventricular assist device (LVAD). This study aimed at describing sleep quality and depression pre and 6 months post LVAD implantation, examining the change in sleep quality and depression over time, and exploring the relationships among sleep quality and depression. An observational research design was used in this study involving 23 patients with LVADs. Patients' demographics, clinical characteristics, subjective and objective sleep data, and depression were collected pre and 6 months post-LVAD implantation hospitalization. Descriptive and inferential statistics were employed in data analysis. We found that poor sleep quality and depression were highly prevalent during pre and post LVAD. Comparing pre to post LVAD, there was a significant change in depression, sleep efficiency, and sleep quality. Differences between sleep quality and depression scores pre to post LVAD were negatively correlated, although there were positive correlations between depression sleep quality scores. These findings are fundamental to informing future research further to understand the sleep-depression phenomenon in the LVAD population. Research is needed to understand the mechanism of the phenomenon and identify.
植入左心室辅助装置（LVAD）的患者中，睡眠质量差和抑郁仍研究不足。本研究旨在描述 LVAD 植入术前和术后 6 个月的睡眠质量和抑郁情况，考察睡眠质量和抑郁随时间的变化，并探讨睡眠质量和抑郁之间的关系。本研究采用观察性研究设计，共纳入 23 名 LVAD 患者。在 LVAD 植入术前和术后 6 个月的住院期间，收集患者的人口统计学、临床特征、主观和客观睡眠数据以及抑郁情况。采用描述性和推断性统计方法进行数据分析。我们发现，LVAD 植入术前和术后患者的睡眠质量差和抑郁发生率均较高。与 LVAD 植入术前相比，术后患者的抑郁、睡眠效率和睡眠质量均有显著变化。LVAD 植入术前和术后睡眠质量和抑郁评分之间的差异呈负相关，尽管抑郁和睡眠质量评分之间呈正相关。这些发现对于进一步了解 LVAD 人群中的睡眠-抑郁现象具有重要意义。需要开展研究以了解该现象的机制，并确定
