Nantakool Sothida, Prasannarong Mujalin, Srisuwan Tanop, Reanpang Termpong, Apichartpiyakul Poon, Rerkasem Kittipan
Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Department of Radiology, Faculty of Medicine, Chiang Mai University, Mueang, Thailand.
J Vasc Access. 2022 Jan;23(1):123-127. doi: 10.1177/1129729820983177. Epub 2020 Dec 25.
Physical examination (PE) is used to determine if arteriovenous fistula (AVF) meets criteria for first hemodialysis (HD) cannulation in chronic kidney disease (CKD) with HD patients. Three ultrasound (US) based criteria are adopted to investigate maturation: : blood flow ⩾600 milliliters per minute (mL/min), vein diameter ⩾6 millimeters (mm), vein depth ⩽6 mm); : blood flow ⩾500 mL/min, vein diameter ⩾5 mm, vein depth ⩽6 mm; : blood flow ⩾500 mL/min, vein diameter ⩾4 mm, vein depth ⩽6 mm. In Thai, no study determined optimal US criteria for predicting AVF maturation measured by PE before first cannulation. This study examined the significance of these US criteria on the physical AVF maturation in Thai.
Fifty CKD patients, operated brachiocephalic AVF, were enrolled and examined on the operative day and 6 weeks afterwards. PE was evaluated by an experienced vascular surgeon, and US measurements were obtained by an experienced US technologist. Matching mature number between US criteria and PE was computed using McNemar test. Agreement between US criteria and PE was measured using Kappa. Mature and immature discrimination were evaluated by the Receiver Operator Characteristics (ROC) curve and Youden index.
and had higher non-mature matching number than ( < 0.001 both). Regarding Kappa statistics, and agreed with the PE ( < 0.01 both). The ROC curve of and were 0.75 and 0.74, respectively ( <0.01 both). Youden index (maturity and immaturity discriminating performance) of both rules was 0.5 and 0.47, respectively.
and agreed with the PE, with the highest performance of the to predict first successful cannulation in Thai.
体格检查(PE)用于确定动静脉内瘘(AVF)是否符合慢性肾脏病(CKD)需进行首次血液透析(HD)的患者进行HD置管的标准。采用基于超声(US)的三项标准来研究内瘘成熟情况:标准一:血流量≥600毫升/分钟(mL/min),静脉直径≥6毫米(mm),静脉深度≤6毫米(mm);标准二:血流量≥500 mL/min,静脉直径≥5 mm,静脉深度≤6 mm;标准三:血流量≥500 mL/min,静脉直径≥4 mm,静脉深度≤6 mm。在泰国,尚无研究确定首次置管前通过PE测量预测AVF成熟的最佳US标准。本研究探讨了这些US标准对泰国AVF体格成熟的意义。
纳入50例接受肱头AVF手术的CKD患者,在手术当天及术后6周进行检查。由经验丰富的血管外科医生进行PE评估,由经验丰富的US技术人员进行US测量。使用McNemar检验计算US标准与PE之间成熟匹配数。使用Kappa测量US标准与PE之间的一致性。通过受试者操作特征(ROC)曲线和尤登指数评估成熟与未成熟的辨别能力。
标准一和标准二的未成熟匹配数高于标准三(两者均P<0.001)。关于Kappa统计,标准一和标准二与PE一致(两者均P<0.01)。标准一和标准二的ROC曲线分别为0.75和0.74(两者均P<0.01)。两条规则的尤登指数(成熟与未成熟辨别性能)分别为0.5和0.47。
标准一和标准二与PE一致,其中标准一对预测泰国首次成功置管的性能最佳。