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心力衰竭与 COVID-19:两种炎症状态的协同作用?

Heart failure and COVID-19: synergism of two inflammatory conditions?

机构信息

Senior Lecturer in Nurse Education, Department of Adult Nursing, King's College London.

出版信息

Br J Community Nurs. 2021 Jan 2;26(1):18-25. doi: 10.12968/bjcn.2021.26.1.18.

DOI:10.12968/bjcn.2021.26.1.18
PMID:33356934
Abstract

Heart failure as a comorbidity in the older population with COVID-19 poses an additional threat to those affected. Patients with both COVID-19 and heart failure share similar risk factors, which result in magnification of pathological outcomes. These include a common inflammatory pathology and related coagulopathy. Both illnesses pose a risk of arrhythmia. Polypharmacy further complicates safe drug administration and worsens the risk of medication-induced arrhythmia. Additionally, both conditions present challenges regarding attaining and maintaining an appropriate nutritional state. Exploration of the interplay between these factors demonstrates the gravity of the co-existence of these conditions and helps understand the difficulties faced when caring for this patient group. Although care provided to COVID-19 patients is primarily related to symptom presentation, based on the analysis conducted, there are some recommendations for practice in relation to evidence and guidelines when managing heart failure patients in primary care within the context of the COVID-19 pandemic.

摘要

在患有 COVID-19 的老年人群中,心力衰竭是一种合并症,这对患者构成了额外的威胁。同时患有 COVID-19 和心力衰竭的患者具有相似的风险因素,这些因素导致病理结果放大。其中包括共同的炎症病理学和相关的凝血功能障碍。这两种疾病都有发生心律失常的风险。多药治疗进一步使安全用药复杂化,并增加了药物引起心律失常的风险。此外,这两种疾病在获得和维持适当营养状态方面都存在挑战。探讨这些因素之间的相互作用表明了这些疾病共存的严重性,并有助于了解在照顾这群患者时所面临的困难。尽管 COVID-19 患者的护理主要与症状表现有关,但根据进行的分析,在 COVID-19 大流行期间,在初级保健中管理心力衰竭患者时,根据证据和指南,有一些关于实践的建议。

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