Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, the Netherlands.
Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands.
JACC Clin Electrophysiol. 2020 Dec;6(14):1739-1743. doi: 10.1016/j.jacep.2020.09.028.
This study sought to investigate whether pediatric patients with congenital heart disease (CHD) already have atrial conduction disorders early in life. The authors conducted first-in-children epicardial mapping in 10 pediatric patients with CHD undergoing primary open heart surgery. Areas of conduction delay (CD) and block (CB) were present in all patients and were particularly observed at Bachmann's bundle (CD: 4.9%; CB: 2.3%), followed by the right atrium (CD: 3.7%; CB: 1.6%) and, to a lesser degree, the left atrium (CD: 1.8%; CB: 1.0%). Conduction abnormalities may by aggravated over time (e.g., aging, residual lesions, or valvular dysfunction), predisposing these patients to atrial arrhythmias early in life.
本研究旨在探讨先天性心脏病（CHD）患儿在生命早期是否已经存在房性传导障碍。作者对 10 例接受初次心脏直视手术的 CHD 患儿进行了首例儿童心外膜标测。所有患者均存在传导延迟（CD）和传导阻滞（CB）区域，尤其是在 Bachmann 束（CD：4.9%；CB：2.3%），其次是右心房（CD：3.7%；CB：1.6%），程度较轻的是左心房（CD：1.8%；CB：1.0%）。传导异常可能随时间推移而加重（例如，老化、残留病变或瓣膜功能障碍），使这些患者在生命早期易发生房性心律失常。
