Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan.
Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan; Faculty of Sport and Health Sciences, Ryutsu Keizai University, Ibaraki, Japan.
Obes Res Clin Pract. 2021 Jan-Feb;15(1):93-95. doi: 10.1016/j.orcp.2020.11.006. Epub 2021 Jan 7.
Weight reduction by lifestyle modification (i.e., low-calorie diet and/or exercise) decreases arterial stiffness in overweight or obese individuals. We previously demonstrated that weight loss differs depending on the degree of intervention in weight-loss support in a randomized controlled trial (UMIN000001259). However, the effect of different degrees of intervention on arterial stiffness remains unclear.
A total of 188 middle-aged men and women with overweight or obesity (51 ± 7 years, BMI: 29.0 ± 3.2 kg/m) participated in the 6-month trial wherein they were assigned to a low (LI, n = 63), moderate (MI, n = 62), or high intensive intervention (HI, n = 63) group. Initially, one motivational lecture on weight loss was provided to all three groups, whereas educational materials (textbooks, notebooks, and a pedometer) were provided to groups MI and HI. Additionally, the HI group participated in a series of group-based sessions. Body weight and arterial stiffness assessed by brachial-ankle pulse wave velocity (baPWV) were measured at 0, 3, and 6 months. Six-month weight loss was greater in the order of HI, MI, and LI groups. The interventions reduced baPWV in all groups, and the reduction was not significantly different among the groups (114.3 ± 16.3, 82.6 ± 15.2, and 98.8 ± 90.4 cm/s, respectively).
In overweight or obese individuals, different degrees of intervention in weight-loss support affect body weight; however, the extent to which arterial stiffness improves does not differ among support programs.
通过生活方式改变（即低热量饮食和/或运动）来减轻体重可以降低超重或肥胖个体的动脉僵硬程度。我们之前的研究表明，在一项随机对照试验（UMIN000001259）中，体重减轻的程度因体重减轻支持干预的程度而异。然而，不同程度的干预对动脉僵硬的影响尚不清楚。
共有 188 名超重或肥胖的中年男女（51 ± 7 岁，BMI：29.0 ± 3.2 kg/m）参加了为期 6 个月的试验，他们被分为低（LI，n = 63）、中（MI，n = 62）或高强化干预（HI，n = 63）组。最初，所有三组都接受了一次关于减肥的动机讲座，而 MI 和 HI 组还提供了教育材料（教科书、笔记本和计步器）。此外，HI 组还参加了一系列小组会议。在 0、3 和 6 个月时测量肱踝脉搏波速度（baPWV）评估体重和动脉僵硬。6 个月时，体重减轻的程度按 HI、MI 和 LI 组的顺序依次增加。所有组的干预措施均降低了 baPWV，且各组之间的降低程度无显著差异（分别为 114.3 ± 16.3、82.6 ± 15.2 和 98.8 ± 90.4 cm/s）。
在超重或肥胖个体中，体重减轻支持的不同程度的干预会影响体重；然而，支持计划对动脉僵硬改善的程度没有差异。
