Severn School of Anaesthesia, Bristol, UK.
University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Int J Obstet Anesth. 2021 Feb;45:130-132. doi: 10.1016/j.ijoa.2020.11.010. Epub 2020 Dec 2.
Recommendations on vasopressor management during caesarean section under spinal anaesthesia suggest maintaining systolic arterial pressure ≥90% of an accurately measured baseline value. The baseline is often taken as the first reading in the operating room. We hypothesise that this reading may not reflect an accurate baseline value.
A retrospective case note review of 300 non-hypertensive women undergoing caesarean section with neuraxial anaesthesia, including spinal anaesthesia for elective delivery (n=100), and spinal (n=100) and epidural top-up anaesthesia (n=100) for emergency delivery. Systolic arterial pressure values recorded at various time points between the last antenatal visit and the first blood pressure value recorded in the operating room were compared.
There was a stepwise and significant increase in systolic arterial pressure over three time points (last antenatal clinic, morning of surgery, operating room) before elective caesarean section (all P <0.001). In women having emergency caesarean under spinal anaesthesia, a stepwise increase over four time points (last antenatal clinic, first reading in labour, final reading in labour, operating room) was observed. A similar trend was seen over these time points for women having emergency caesarean under epidural top-up, although the systolic blood pressure did not rise during labour.
Using the initial blood pressure reading in the operating room as the baseline value may lead to unnecessary vasopressor use and hypertension. Prospective research is required to clarify which reading represents the most accurate baseline to maintain homeostasis and reduce the hypotensive sequelae of neuraxial anaesthesia for both the mother and fetus.
椎管内麻醉下剖宫产时血管加压药管理的建议建议维持收缩压≥准确测量的基线值的 90%。基线值通常作为手术室中的第一次读数。我们假设该读数可能无法反映准确的基线值。
回顾性分析 300 例非高血压妇女行椎管内麻醉下剖宫产术的病历,包括择期分娩(n=100)的脊髓麻醉、紧急分娩时的脊髓(n=100)和硬膜外追加麻醉(n=100)。比较最后一次产前就诊和手术室记录的第一个血压值之间不同时间点的收缩压值。
在择期剖宫产前,收缩压在三个时间点(最后一次产前门诊、手术当天早上、手术室)呈逐步显著升高(均 P<0.001)。在脊髓麻醉下进行紧急剖宫产的妇女中,在四个时间点(最后一次产前门诊、分娩时第一次读数、分娩时最后一次读数、手术室)观察到收缩压呈逐步升高。在硬膜外追加麻醉下进行紧急剖宫产的妇女中也观察到类似的趋势,尽管在分娩期间收缩压没有升高。
将手术室中的初始血压读数用作基线值可能导致不必要的血管加压药使用和高血压。需要前瞻性研究来阐明哪种读数代表最准确的基线值,以维持母体和胎儿的内稳态并减少神经轴麻醉的低血压后遗症。