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注射吸毒导致的感染性心内膜炎:加拿大心脏外科医生调查。

Infective Endocarditis Secondary to Injection Drug Use: A Survey of Canadian Cardiac Surgeons.

机构信息

Division of Cardiac Surgery, St Michael's Hospital, University of Toronto, Toronto, Canada.

Division of Cardiovascular Surgery, University of British Columbia, Vancouver, Canada.

出版信息

Ann Thorac Surg. 2021 Nov;112(5):1460-1467. doi: 10.1016/j.athoracsur.2020.12.003. Epub 2021 Jan 6.

DOI:10.1016/j.athoracsur.2020.12.003
PMID:33358887
Abstract

BACKGROUND

Injection drug use-associated infective endocarditis (IDU-IE) is a growing epidemic. The objective of this survey was to identify the beliefs and practice patterns of Canadian cardiac surgeons regarding surgical management of IDU-IE.

METHODS

A 30-question survey was developed by a working group and distributed to all practicing adult cardiac surgeons in Canada. Data were analyzed using descriptive statistics.

RESULTS

Of 146 surgeons, 94 completed the survey (64%). Half of surgeons (49%) would be less likely to operate on patients with IE if associated with IDU. In the case of prosthetic valve IE owing to continued IDU, 36% were willing to reoperate once and 14% were willing to reoperate twice or more. Most surgeons required commitments from patients before surgery (73%), and most referred patients to addiction services (81%). Some surgeons would offer a Ross procedure (10%) or homograft (8%) for aortic valve IE, and 47% would consider temporary mechanical circulatory support. Whereas only 17% of surgeons worked at an institution with an endocarditis team, 71% agreed that there was a need for one at each institution. Most surgeons supported the development of IDU-IE-specific guidelines (80%).

CONCLUSIONS

Practice patterns and surgical management of IDU-IE vary considerably across Canada. Areas of clinical unmet needs include the development of a formal addiction services referral protocol for patients, the development of an interdisciplinary endocarditis team, as well as the creation of IDU-IE clinical practice guidelines.

摘要

背景

注射吸毒相关性感染性心内膜炎(IDU-IE)是一种日益严重的流行疾病。本调查的目的是确定加拿大心脏外科医生对 IDU-IE 手术治疗的信念和实践模式。

方法

由一个工作组制定了 30 个问题的调查问卷,并分发给加拿大所有执业的成人心脏外科医生。使用描述性统计方法分析数据。

结果

在 146 名外科医生中,有 94 名(64%)完成了调查。一半的外科医生(49%)如果与 IDU 相关,他们不太可能对 IE 患者进行手术。对于因持续 IDU 导致的人工瓣膜 IE,36%的外科医生愿意进行一次再手术,14%的外科医生愿意进行两次或更多次再手术。大多数外科医生在手术前要求患者做出承诺(73%),并将大多数患者转介给成瘾服务(81%)。一些外科医生会为主动脉瓣 IE 提供 Ross 手术(10%)或同种异体移植(8%),47%的外科医生会考虑使用临时机械循环支持。尽管只有 17%的外科医生在有 IE 团队的机构工作,但 71%的人认为每个机构都需要一个 IE 团队。大多数外科医生支持制定 IDU-IE 特定指南(80%)。

结论

加拿大各地 IDU-IE 的实践模式和手术管理差异很大。临床未满足需求的领域包括为患者制定正式的成瘾服务转介协议、建立跨学科 IE 团队,以及制定 IDU-IE 临床实践指南。

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