Maimonides Medical Center, Department of Radiology, 4802 10th Avenue, Brooklyn, New York 11219, United States of America.
Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road Piscataway, NJ 08854, United States of America; Saint Barnabas Medical Center, 94 Old Short Hills Road, Livingston, NJ 07039, United States of America.
Am J Emerg Med. 2021 Jul;45:682.e7-682.e9. doi: 10.1016/j.ajem.2020.12.025. Epub 2020 Dec 15.
Ketamine is a versatile analgesic that has become an increasingly popular recreational drug. Chronic ketamine use has been found to cause biliary duct damage and bladder dysfunction. Ketamine-induced cholangiopathy and ulcerative cystitis are uncommon diagnoses presenting with nonspecific symptoms, creating diagnostic challenges for emergency physicians. We report a case of a teenage patient with the rare simultaneous presentation of ketamine-induced cholangiopathy and ulcerative cystitis. Due to increased recreational and chronic ketamine use, cases of ketamine-induced cholangiopathy and ulcerative cystitis are likely to rise with the increased knowledge, awareness, and reporting of these entities by radiologists and emergency physicians.
氯胺酮是一种用途广泛的镇痛药，已成为一种越来越受欢迎的娱乐性药物。研究发现，慢性使用氯胺酮会导致胆管损伤和膀胱功能障碍。氯胺酮引起的胆管病和溃疡性膀胱炎是不常见的诊断，其表现为非特异性症状，给急诊医生的诊断带来挑战。我们报告了一例青少年患者同时患有罕见的氯胺酮引起的胆管病和溃疡性膀胱炎。由于娱乐性和慢性使用氯胺酮的增加，随着放射科医生和急诊医生对这些疾病的认识、意识和报告的增加，氯胺酮引起的胆管病和溃疡性膀胱炎的病例可能会增加。
