Mahmoud Waleed, El Ansari Walid, Hassan Sara, Alatasi Sali, Almerekhi Haya, Junejo Kulsoom
Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.
Department of Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; College of Medicine, Qatar University, Doha, Qatar; School of Health and Education, University of Skovde, Skovde, Sweden.
Int J Surg Case Rep. 2021 Jan;78:145-150. doi: 10.1016/j.ijscr.2020.11.139. Epub 2020 Dec 2.
Mammary hamartoma is a benign rare tumour occurring in both sexes, with size range mostly between 2-4 cm. Giant breast hamartoma (GMH) is very rare and can reach unexpected sizes in women.
A 26 year old Egyptian female presented with left breast lump since 3 years, gradually increasing in size, with no other associated complaints. No family history of breast cancer, she did not smoke or consume alcohol, and had no past medical history. Examination revealed a large soft freely mobile mass (12 × 9 cm) in the lower outer quadrant of the left breast at the 3-6 o'clock position. There were no palpable axillary lymph nodes in both sides. Nipples and right breast were normal.
The diagnosis of GMH can be made by examination and imaging only. The specific features that appear in mammogram and ultrasound can be used to reduce the need for core biopsy in hamartoma. Wide local excision is curative. We include a review of the literature of cases of GMH > 10 cm published during the last 15 years.
A non-invasive mammogram and ultrasound provide sufficient evidence of the tumour, hence core biopsy might not be critically required. However, if a breast hamartoma is still clinically suspected but with inconclusive or unequivocal mammographic and ultrasonographic features or if there is suspicion of dysplasia, then invasive core biopsy is justified. Recurrence is low and prognosis is good.
乳腺错构瘤是一种发生于两性的罕见良性肿瘤,大小范围大多在2 - 4厘米之间。巨大乳腺错构瘤(GMH)非常罕见,在女性中可达到意想不到的大小。
一名26岁的埃及女性自3年前起出现左乳肿块,肿块大小逐渐增大,无其他相关症状。无乳腺癌家族史,她不吸烟、不饮酒,也无既往病史。检查发现左乳外下象限3 - 6点位置有一个大的、质地柔软、可自由活动的肿块(12×9厘米)。双侧腋窝均未触及肿大淋巴结。乳头及右乳正常。
GMH仅通过检查和影像学检查即可诊断。乳腺钼靶和超声检查中出现的特定特征可用于减少错构瘤的粗针活检需求。广泛局部切除可治愈。我们纳入了对过去15年发表的GMH>10厘米病例的文献综述。
无创性乳腺钼靶和超声检查可为肿瘤提供充分证据,因此可能并非急需粗针活检。然而,如果临床上仍怀疑乳腺错构瘤,但乳腺钼靶和超声检查特征不明确或不确定,或者怀疑有发育异常,则进行有创粗针活检是合理的。复发率低,预后良好。