Tinti Stefania, Cassani Gaia, Pinna Ines, Alberti Annalisa, Destrebecq Anne
Dipartimento di Biomedicina e Prevenzione, Università di Roma "Tor Vergata" - ASST-Rhodense Garbagnate Milanese, Milano.
Infermieristica, Università di Milano.
Recenti Prog Med. 2020 Dec;111(12):722-732. doi: 10.1701/3509.34963.
Head-neck neoplasms are the fifth most common cancer. Head-neck patients are particularly exposed to quality of life impairment due to the central anatomical-functional role of this region in primary functions such as breathing, swallowing and phonation. Many patients are already at an advanced stage of the disease at the time of diagnosis and their prognosis remains unfavourable despite new treatment options. They face daily with multiple and simultaneous symptoms. In 20% of cases the average survival is only 5 months, making it appropriate to take charge early for the important need of palliative care. The aim of this review is to deepen the knowledge concerning the neoplasms of the head-neck district, with particular reference to the symptoms and quality of life of people in advanced stage and in palliative care. The literature review was performed through CINAHL, Cochrane Library, Embase, PsycINFO, PubMed, Scopus and Web of Science. The research identified 9 studies that met the inclusion criteria. The results of the studies showed the prevalent symptoms of dyspnea, fatigue, nutrition and oral problems, pain, insomnia, anxiety and depression. Oral nutrition could be compromised, producing weight loss and malnutrition. In such a condition, the enteral route could be necessary. The impact of the symptoms was greater for those who could not maintain adequate nutrition and was a predictor of reduced food intake, weight loss and survival. Malnutrition influenced the performance status and quality of life which seemed to remain unchanged as the end of life approached. Mucositis, dysphagia and xerostomia had a strong association. Dysphagia was related to dysphonia. A worsening of emotional distress was shown in relation to the female gender and the tumor site. Head-neck cancer had a strong impact on the quality of life. Patients considere dyspnea, dysphonia, mobility problems, anger and weakness as the most important issues. Earlier interventions could allow a partial and temporary improvement of quality of life compatible with the patient's conditions. Nursing care involves multidimensional assessment and an early individualized, symptom-driven and needs-oriented approach.
头颈肿瘤是第五大常见癌症。由于该区域在呼吸、吞咽和发声等主要功能中起着核心解剖功能作用,头颈癌患者特别容易受到生活质量受损的影响。许多患者在诊断时就已处于疾病晚期,尽管有新的治疗选择,但其预后仍然不佳。他们每天都面临多种并发症状。在20%的病例中,平均生存期仅为5个月,因此尽早满足姑息治疗的重要需求是合适的。本综述的目的是加深对头颈区肿瘤的认识,特别是晚期和接受姑息治疗患者的症状和生活质量。通过CINAHL、Cochrane图书馆、Embase、PsycINFO、PubMed、Scopus和科学网进行了文献综述。该研究确定了9项符合纳入标准的研究。研究结果显示,常见症状包括呼吸困难、疲劳、营养和口腔问题、疼痛、失眠、焦虑和抑郁。口服营养可能会受到影响,导致体重减轻和营养不良。在这种情况下,可能需要采用肠内营养途径。对于那些无法维持充足营养的患者,症状的影响更大,并可预测食物摄入量减少、体重减轻和生存期缩短。营养不良影响了身体功能状态和生活质量,但在生命末期似乎保持不变。口腔炎、吞咽困难和口干有很强的关联性。吞咽困难与发声困难有关。女性性别和肿瘤部位与情绪困扰的加重有关。头颈癌对生活质量有很大影响。患者认为呼吸困难、发声困难、行动问题、愤怒和虚弱是最重要的问题。早期干预可以使生活质量得到部分和暂时的改善,与患者的病情相适应。护理工作包括多维度评估以及早期个体化、症状驱动和需求导向的方法。