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病例报告:阻塞性睡眠呼吸暂停低通气综合征诱发的异态睡眠重叠障碍:一例病例报告及文献综述

Case Report: Parasomnia Overlap Disorder Induced by Obstructive Sleep Hypopnea Apnea Syndrome: A Case Report and Literature Review.

作者信息

Sun Yun, Li Jie, Zhang Xinjun, Jiao Qingyan, Yang Shutong, Ji Lijie

机构信息

Department of Sleep Medicine, Tianjin Anding Hospital, Tianjin, China.

Institute of Mental Health, Tianjin Anding Hospital, Tianjin, China.

出版信息

Front Neurosci. 2020 Dec 10;14:578171. doi: 10.3389/fnins.2020.578171. eCollection 2020.

DOI:10.3389/fnins.2020.578171
PMID:33362452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7758532/
Abstract

Obstructive sleep apnea hypopnea syndrome (OSAHS) and parasomnia overlap disorder (POD) are types of sleep disorders. When the symptoms of both conditions coexist, the POD symptoms are most likely caused by OSAHS. In these cases, the symptoms of POD will be relieved when OSAHS is effectively treated. We refer to these cases as symptomatic POD (related to OSAHS), which differs in pathophysiology, complications, and treatment from idiopathic POD. It is important to note that the treatment for idiopathic POD may aggravate the symptoms of OSAHS. In this case, we used video polysomnography (v-PSG) on a POD patient with suspected OSAHS to distinguish idiopathic POD from symptomatic POD, to inform the appropriate treatment course. The video results and clinical features lead us to diagnose symptomatic POD, and we treated the patient with auto-set continuous positive airway pressure to address their OSAHS. This course of treatment resolved all POD-related symptoms. Here, we discuss this case and review the relevant literature. This report highlights the importance of the use of v-PSG in the clinical diagnosis, differential diagnosis, and subsequent treatment of POD.

摘要

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)和异态睡眠重叠障碍(POD)是睡眠障碍的类型。当这两种病症的症状同时存在时,POD症状很可能由OSAHS引起。在这些情况下,OSAHS得到有效治疗时,POD症状将会缓解。我们将这些病例称为症状性POD(与OSAHS相关),其在病理生理学、并发症和治疗方面与特发性POD不同。需要注意的是,特发性POD的治疗可能会加重OSAHS的症状。在此病例中,我们对一名疑似OSAHS的POD患者进行了视频多导睡眠图(v-PSG)检查,以区分特发性POD和症状性POD,从而确定合适的治疗方案。视频检查结果和临床特征使我们诊断为症状性POD,并使用自动调压持续气道正压通气治疗该患者的OSAHS。这一治疗过程消除了所有与POD相关的症状。在此,我们讨论该病例并回顾相关文献。本报告强调了v-PSG在POD临床诊断、鉴别诊断及后续治疗中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/32db2f29a0ca/fnins-14-578171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/40fa21d41820/fnins-14-578171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/65af1fac2513/fnins-14-578171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/32db2f29a0ca/fnins-14-578171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/40fa21d41820/fnins-14-578171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/65af1fac2513/fnins-14-578171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e4/7758532/32db2f29a0ca/fnins-14-578171-g003.jpg

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Parasomnia overlap disorder with adolescent-onset presumed REM sleep behavior disorder converting to Parkinson's disease after 48 years.失眠症重叠障碍伴青少年起病的 REM 睡眠行为障碍,48 年后转化为帕金森病。
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