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氯吡格雷所致肝损伤:一例病例报告及文献复习

Clopidogrel-induced liver damage: A case report and review of the literature.

作者信息

Eslami Vahid, Gheymati Azin

机构信息

Shahid Beheshti University of Medical Sciences, Cardiovascular Research Center Tehran Iran.

Tehran University of Medical Sciences, School of Pharmacy Tehran Iran.

出版信息

Clin Case Rep. 2020 Sep 16;8(12):3024-3027. doi: 10.1002/ccr3.3324. eCollection 2020 Dec.

Abstract

Liver damage is a rare side effect of clopidogrel. That is reversible in most cases. Considering the widespread use of this medication in cardiovascular diseases, the management of hepatotoxicity requires further meticulous investigation.

摘要

肝损伤是氯吡格雷一种罕见的副作用,在大多数情况下是可逆的。鉴于这种药物在心血管疾病中的广泛应用,肝毒性的管理需要进一步细致研究。

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An idiosyncratic reaction to clopidogrel.对氯吡格雷的特异反应。
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本文引用的文献

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Significant increase in clopidogrel use across U.S. children's hospitals.
Pediatr Cardiol. 2011 Feb;32(2):167-75. doi: 10.1007/s00246-010-9836-0. Epub 2010 Dec 7.
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Fatal liver injury associated with clopidogrel.氯吡格雷相关致死性肝损伤。
Fundam Clin Pharmacol. 2010 Aug;24(4):433-5. doi: 10.1111/j.1472-8206.2009.00791.x. Epub 2009 Nov 5.
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Clopidogrel-induced mixed hepatocellular and cholestatic liver injury.
Am J Ther. 2000 Sep;7(5):317-8. doi: 10.1097/00045391-200007050-00009.

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