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与具有肾意义的单克隆丙种球蛋白病相关的骨髓浆细胞中的轻链阳性杆状包涵体。

Light chain-positive rod-like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance.

作者信息

Okawara Sayoko, Bando Kenichiro, Tsukada Junichi

机构信息

Hematology University of Occupational and Environmental Health Kitakyushu Japan.

The Second Department of Internal Medicine University of Occupational and Environmental Health Kitakyushu Japan.

出版信息

Clin Case Rep. 2020 Sep 21;8(12):3621-3622. doi: 10.1002/ccr3.3362. eCollection 2020 Dec.

DOI:10.1002/ccr3.3362
PMID:33364007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7752359/
Abstract

Rod-like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ-light chain positivity of rod-like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bortezomib was also observed.

摘要

在具有肾脏意义的单克隆丙种球蛋白病或多发性骨髓瘤病例中，杆状包涵体很少被描述。我们病例中的关键发现是浆细胞中杆状包涵体的κ轻链强阳性，这证实了它们的免疫球蛋白性质。还观察到硼替佐米的治疗益处。

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Auer rod-like inclusions in multiple myeloma.多发性骨髓瘤中的奥厄小体样包涵体。
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