Raja Mohummad Hassan Raza, Javed Muhammad Abdullah, Zubairi Ali Bin Sarwar
Medical College Aga Khan University Karachi Pakistan.
Section of Pulmonary and Critical Care Medicine, Department of Medicine Aga Khan University Karachi Pakistan.
Respirol Case Rep. 2020 Dec 23;9(2):e00705. doi: 10.1002/rcr2.705. eCollection 2021 Feb.
We report the case of a 60-year-old woman, presenting with left vocal cord paralysis (VCP). Diagnostic evaluation revealed sarcoidosis to be the underlying pathology. Computed tomography (CT) scans exhibited enlarged subcarinal, pretracheal, and prevascular lymph nodes as the possible mechanism of left VCP through compression of the left recurrent laryngeal nerve. Initial treatment with oral prednisolone and azathioprine led to remission of symptoms; however, tapering of dosage led to relapse of cough without any signs of VCP. The dosage of prednisolone was further boosted, leading to complete remission. A review of literature reveals 20 cases have been reported to date, with all but one involving the left vocal cord. This is the first reported case, with a relapse of the disease without a relapse of VCP, indicating the rarity of sarcoidosis-associated VCP.
我们报告了一例60岁女性，表现为左侧声带麻痹（VCP）。诊断评估显示潜在病理为结节病。计算机断层扫描（CT）显示隆突下、气管前和血管前淋巴结肿大，这可能是通过压迫左侧喉返神经导致左侧VCP的机制。口服泼尼松龙和硫唑嘌呤的初始治疗使症状缓解；然而，剂量逐渐减少导致咳嗽复发，且无VCP的任何迹象。泼尼松龙剂量进一步增加，导致完全缓解。文献回顾显示，迄今为止已报告20例，除1例外均累及左侧声带。这是首例报告的疾病复发但VCP未复发的病例，表明结节病相关VCP的罕见性。
