Fernandez H, Rainhorn J D, Papiernik E, Bellet D, Frydman R
Department of Obstetrics and Gynecology, Béclère Hospital, Clamart, France.
Obstet Gynecol. 1988 Feb;71(2):171-4.
Fourteen patients with ampullary tubal pregnancy confirmed by laparoscopy were initially managed conservatively. Serum human chorionic gonadotropin (hCG) levels were measured daily and strict clinical monitoring performed. In nine patients (64%), the tubal pregnancy spontaneously resolved. In four cases (29%), surgery was ultimately necessary. One patient with a coexistent intra- and extrauterine pregnancy was also successfully managed conservatively. There was a high probability of spontaneous resolution of the pregnancy when the serum hCG level at diagnosis was less than 1000 mIU/mL. Hysterosalpingography was performed after the spontaneous resolution of the tubal pregnancies. Tubal patency was demonstrated in all six patients, and three are currently pregnant. We conclude that conservative therapy allows spontaneous resolution of certain types of ectopic pregnancy.
14例经腹腔镜确诊为壶腹部输卵管妊娠的患者最初接受保守治疗。每天检测血清人绒毛膜促性腺激素（hCG）水平，并进行严格的临床监测。9例患者（64%）输卵管妊娠自然消退。4例患者（29%）最终需要手术治疗。1例合并宫内和宫外妊娠的患者也成功接受了保守治疗。诊断时血清hCG水平低于1000 mIU/mL时，妊娠自然消退的可能性很高。输卵管妊娠自然消退后进行了子宫输卵管造影。所有6例患者均显示输卵管通畅，其中3例目前已怀孕。我们得出结论，保守治疗可使某些类型的异位妊娠自然消退。
