Meng Xiaduo, Xie Yue, Gu Xiaobin, Zheng Youle, Liu Yunjian, Li Yingxin, Wang Lu, Zhou Xuan, Zuo Zhicai, Yang Guangyou
Department of Parasitology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
Mitochondrial DNA B Resour. 2019 Sep 13;4(2):2999-3001. doi: 10.1080/23802359.2019.1666042.
The dog roundworm (Nematoda: Toxocaridae) is an important zoonotic parasitic nematode and cause toxocariasis in human with a worldwide distribution. Herein, the complete mitochondrial genome of a representative of this nematode from USA was determined through next generation sequencing platform. The whole genome was 14,309 bp in size and encoded 12 protein-coding genes, 22 transfer RNAs, and 2 ribosomal RNAs. Phylogeny showed that although from USA and Australia were more closely related to each other than to that from Chinese, three isolates clustered together and formed paraphyletic relationships with and , supporting them as sister species among the family Toxocaridae. These cumulative mitochondrial DNA data should contribute to a better understanding of the phylogenetic relationship of this species.
犬弓首蛔虫(线虫纲:弓首蛔科)是一种重要的人兽共患寄生线虫,可在全球范围内导致人类患弓首蛔虫病。在此,通过下一代测序平台确定了来自美国的该线虫一个代表性样本的完整线粒体基因组。全基因组大小为14,309 bp,编码12个蛋白质编码基因、22个转运RNA和2个核糖体RNA。系统发育分析表明,尽管来自美国和澳大利亚的样本彼此之间的亲缘关系比与来自中国的样本更近,但三个分离株聚在一起,与其他样本形成了并系关系,支持它们作为弓首蛔科中的姐妹物种。这些累积的线粒体DNA数据应有助于更好地理解该物种的系统发育关系。