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治疗青光眼的仿制药与品牌药:争论仍在继续。

Generics versus brand-named drugs for glaucoma: the debate continues.

机构信息

Glaucoma Services, Fortis Memorial Research Institute, Gurugram, Haryana, India.

Shah Satnam Ji Speciality Hospitals, Sirsa, Haryana, India.

出版信息

Rom J Ophthalmol. 2020 Jul-Sep;64(3):239-244.

Abstract

There are three options for a given class of drugs, including brand name drugs, generic and branded generic drugs. Brand name drugs are costlier as compared to generic and branded generic drugs because they are innovator molecules developed by a company after many years of research and come into the market with a patent, whereas branded generic drugs are produced by a different company once the patent of innovator company expires. Given that glaucoma is a chronic, largely asymptomatic disease, the choice of drugs is extremely important: the duration of medication is often lifelong, and the cost of drugs, side effects and efficacy affect compliance and adherence to therapy. This review is a brief overview of the available brand name and branded generic drugs for the management of glaucoma, in terms of efficacy and side effect profiles. It also aimed to guide rational and pragmatic drug choices in different clinical scenarios.

摘要

对于某一类药物,有三种选择,包括品牌药物、仿制药和品牌仿制药。与仿制药和品牌仿制药相比,品牌药物的价格更高,因为它们是公司经过多年研究开发的创新分子,具有专利,并在市场上推出。而品牌仿制药则是在创新公司的专利过期后由另一家公司生产的。由于青光眼是一种慢性、大多无症状的疾病,药物的选择非常重要:药物治疗的时间往往是终身的,药物的成本、副作用和疗效会影响患者的依从性和对治疗的坚持。本综述简要概述了可用于治疗青光眼的品牌药物和品牌仿制药,从疗效和副作用方面进行了介绍。它还旨在指导在不同临床情况下合理和务实的药物选择。

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