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严重低血糖症相关对话和反应调查(CRASH):来自全球 1 型糖尿病或胰岛素治疗 2 型糖尿病患者及其照护者的德国队列调查结果。

Conversations and Reactions Around Severe Hypoglycaemia (CRASH): Results from the German Cohort of a Global Survey of People with Type 1 Diabetes or Insulin-Treated Type 2 Diabetes and Caregivers.

机构信息

Lilly Deutschland GmbH, Bad Homburg, Germany.

HaaPACS GmbH, Schriesheim, Germany.

出版信息

Exp Clin Endocrinol Diabetes. 2022 Mar;130(3):145-155. doi: 10.1055/a-1310-7963. Epub 2020 Dec 23.

Abstract

BACKGROUND

A global cross-sectional survey (CRASH) was designed to provide information about the experiences of people with diabetes (PWD) and their caregivers in relation to severe hypoglycaemic events.

METHODS

Adults with type 1 diabetes or insulin-treated type 2 diabetes who had experienced one or more severe hypoglycaemic events within the past 3 years, and adult caregivers for such people, were recruited from medical research panels using purposive sampling. We present here results from Germany.

RESULTS

Approximately 100 individuals in each of the four participant groups completed a 30-minute online survey. Survey results indicated that the most recent severe hypoglycaemic event made many participants feel scared (80.4%), unprepared (70.4%), and/or helpless (66.5%). Severe hypoglycaemia was discussed by healthcare professionals at every visit with only 20.2% of participants who had ever had this conversation, and 53.5% of participants indicated that their insulin regimen had not changed following their most recent event. 37.1% of PWD/people with diabetes cared for by caregivers owned a glucagon kit at the time of survey completion.

CONCLUSIONS

The survey identified areas for improvement in the prevention and management of severe hypoglycaemic events. For healthcare professionals, these include enquiring more frequently about severe hypoglycaemia and adjusting blood glucose-lowering medication after a severe hypoglycaemic event. For individuals with diabetes and their caregivers, potential improvements include ensuring availability of glucagon at all times. Changes in these areas could lead not only to improved patient wellbeing but also to reduced use of emergency services/hospitalisation and, consequently, lower healthcare costs.

摘要

背景

一项全球横断面调查(CRASH)旨在提供有关糖尿病患者(PWD)及其护理人员在严重低血糖事件方面的经验信息。

方法

从医学研究小组中采用目的性抽样,招募了过去 3 年内经历过一次或多次严重低血糖事件的 1 型糖尿病或接受胰岛素治疗的 2 型糖尿病成人患者,以及这些患者的成年护理人员。在此,我们展示了来自德国的结果。

结果

在四个参与者组中,大约每组有 100 人完成了一项 30 分钟的在线调查。调查结果表明,最近的严重低血糖事件使许多参与者感到害怕(80.4%)、毫无准备(70.4%)和/或无助(66.5%)。只有 20.2%的曾有过此类谈话的参与者会在每次就诊时与医护人员讨论严重低血糖事件,53.5%的参与者表示他们的胰岛素治疗方案在最近一次事件后没有改变。在调查完成时,37.1%的 PWD/受护理者拥有胰高血糖素套件。

结论

该调查确定了在预防和管理严重低血糖事件方面需要改进的领域。对于医护人员而言,这些措施包括更频繁地询问严重低血糖事件,并在发生严重低血糖事件后调整血糖降低药物。对于糖尿病患者及其护理人员,潜在的改进措施包括确保随时可以获得胰高血糖素。这些方面的改变不仅可以改善患者的健康状况,还可以减少对紧急服务/住院的使用,从而降低医疗保健成本。

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