Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
Department of Dental Materials and Prosthodontics, Sao Paulo State University (UNESP), Araçatuba, Brazil.
J Esthet Restor Dent. 2021 Jun;33(4):567-582. doi: 10.1111/jerd.12699. Epub 2020 Dec 24.
Nanotechnology has progressed significantly and particles as small as 3 nm are being employed in resin-based restorative materials to improve clinical performance. The goal of this review is to report the progress of nanotechnology in Restorative Dentistry by reviewing the advantages, limitations, and applications of resin-based restorative materials with nanoparticles.
A literature review was conducted using PubMed/Medline, Scopus and Embase databases. In vitro, in vivo and in situ research studies published in English between 1999 and 2020, and which focused on the analysis of resin-based restorative materials containing nanoparticles were included.
A total of 140 studies were included in this review. Studies reported the effect of incorporating different types of nanoparticles on adhesive systems or resin composites. Mechanical, physical, and anti-bacterial properties were described. The clinical performance of resin-based restorative materials with nanoparticles was also reported.
The high surface area of nanoparticles exponentially increases the bioactivity of materials using bioactive nanofillers. However, the tendency of nanoparticles to agglomerate, the chemical instability of the developed materials and the decline of rheological properties when high ratios of nanoparticles are employed are some of the obstacles to overcome in the near future.
In spite of the recent advancements of nanotechnology in resin-based restorative materials, some challenges need to be overcome before new nano-based restorative materials are considered permanent solutions to clinical problems.
纳米技术取得了显著进展，目前正将粒径小至 3nm 的颗粒应用于树脂基修复材料中，以改善临床性能。本综述的目的是通过综述具有纳米颗粒的树脂基修复材料的优点、局限性和应用，来报告纳米技术在修复牙科领域的进展。
使用 PubMed/Medline、Scopus 和 Embase 数据库进行文献回顾。纳入了 1999 年至 2020 年期间以分析含有纳米颗粒的树脂基修复材料为重点、发表于英文期刊的体外、体内和原位研究。
本综述共纳入了 140 项研究。研究报告了将不同类型的纳米颗粒掺入到粘结系统或树脂复合材料中对其产生的影响。描述了机械性能、物理性能和抗菌性能。还报告了含有纳米颗粒的树脂基修复材料的临床性能。
纳米颗粒的高表面积可通过使用生物活性纳米填料使材料的生物活性呈指数级增长。然而，纳米颗粒团聚的趋势、开发材料的化学不稳定性以及当纳米颗粒的比例较高时流变性能的下降，是未来需要克服的一些障碍。
尽管纳米技术在树脂基修复材料方面取得了最新进展，但在将新型纳米基修复材料视为解决临床问题的永久解决方案之前，还需要克服一些挑战。
