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中高级别（预后不良）非霍奇金淋巴瘤复发为低级别（预后良好）非霍奇金淋巴瘤。4例报告。

Relapse of intermediate or high-grade (unfavorable) non-Hodgkin's lymphoma as a low-grade (favorable) Non-Hodgkin's lymphoma. Report of four cases.

作者信息

Head D R, Avakian J, Kjeldsberg C R, Cerezo L

机构信息

Department of Pathology, University of Utah Medical Center, Salt Lake City 84132.

出版信息

Am J Clin Pathol. 1988 Jan;89(1):106-8. doi: 10.1093/ajcp/89.1.106.

DOI:10.1093/ajcp/89.1.106
PMID:3337045
Abstract

The authors present four cases of low-grade (favorable) non-Hodgkin's lymphoma appearing after successful treatment of intermediate or high-grade (unfavorable) non-Hodgkin's lymphoma. In each case, the patient had intermediate or high-grade non-Hodgkin's lymphoma, received multiagent chemotherapy, and entered complete remission lasting one to six years. Each patient had a relapse with low-grade non-Hodgkin's lymphoma. Possible explanations and therapeutic implications are discussed.

摘要

作者报告了4例在中高级（预后不良）非霍奇金淋巴瘤成功治疗后出现的低级（预后良好）非霍奇金淋巴瘤病例。在每例病例中，患者均患有中高级非霍奇金淋巴瘤，接受了多药化疗，并进入持续1至6年的完全缓解期。每名患者均复发为低级非霍奇金淋巴瘤。文中讨论了可能的解释及治疗意义。

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