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90 岁及以上社区居住的超高龄老年人的死亡和健康相关因素:一项为期 10 年的随访研究。

Mortality-and Health-Related Factors in a Community-Dwelling of Oldest-Older Adults at the Age of 90: A 10-Year Follow-Up Study.

机构信息

Department of Translational Research, School of Dental Medicine, Tsurumi University, Yokohama 230-8501, Japan.

Chiba Prefectural University of Health Sciences, Chiba 261-0014, Japan.

出版信息

Int J Environ Res Public Health. 2020 Dec 21;17(24):9584. doi: 10.3390/ijerph17249584.

Abstract

Mortality is obviously intended for epidemiological studies of community-dwelling older adults. There are several health-related factors associated with nutritional status and mortality. The aim of this study was to elucidate the risk factor for mortality in community-dwelling oldest-older adults at the age of 90 and clarify the structure of health-related factors associated with mortality. A 10-year follow-up study was performed for 93 subjects at the age of 90. The mean and median of their survival days were 2373 and 2581 days for women, and 1694 and 1793 days for men. By Cox's proportional hazards model, health-related factors associated with mortality were self-assessed for chewing ability, activities of daily living (ADLs), serum albumin, total cholesterol, serum creatinine, and gripping power for women but not for men. These factors interacted with each other, and the association of these factors was different in women and men. Self-assessed chewing ability was a powerful risk factor for mortality in women at the age of 90. It acted independently from nutritional status. For older adults, addressing healthy food choices together with improved oral functions is useful. However, risk factors for mortality may depend on the life stage of subjects. To investigate the risk factor for the mortality, the life course approach is necessary.

摘要

死亡率显然是为社区居住的老年人进行流行病学研究而设计的。有几个与营养状况和死亡率相关的健康相关因素。本研究的目的是阐明 90 岁及以上社区居住的最年长老年人的死亡风险因素,并阐明与死亡率相关的健康相关因素的结构。对 93 名 90 岁的受试者进行了 10 年的随访研究。女性的平均和中位数存活天数分别为 2373 天和 2581 天,男性分别为 1694 天和 1793 天。通过 Cox 比例风险模型,与死亡率相关的健康相关因素为女性的自我评估咀嚼能力、日常生活活动(ADL)、血清白蛋白、总胆固醇、血清肌酐和握力,但对男性没有影响。这些因素相互作用,这些因素在女性和男性中的关联不同。自我评估的咀嚼能力是女性 90 岁时死亡的一个强有力的风险因素。它独立于营养状况。对于老年人来说,一起改善健康的食物选择和口腔功能是有用的。然而,死亡风险因素可能取决于受试者的生命阶段。为了研究死亡的风险因素,需要采用生命历程的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7251/7768389/ceddee2c0769/ijerph-17-09584-g001.jpg

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