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代谢减重手术治疗阻塞性睡眠呼吸暂停低通气综合征:文献回顾与潜在机制。

Metabolic bariatric surgery as a treatment for obstructive sleep apnea hypopnea syndrome: review of the literature and potential mechanisms.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China; Sleep Medicine Center, Zhongnan Hospital of Wuhan University, Wuhan, China.

Department of Otorhinolaryngology, Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China; Sleep Medicine Center, Zhongnan Hospital of Wuhan University, Wuhan, China.

出版信息

Surg Obes Relat Dis. 2021 Jan;17(1):215-220. doi: 10.1016/j.soard.2020.09.019. Epub 2020 Sep 23.

Abstract

Obstructive sleep apnea hypopnea syndrome (OSAHS) is closely related to obesity and can cause multiple organs and systems damage. Metabolic bariatric surgery (MBS) is presently the only long-term effective treatment and an important strategy for severely obese population, which also provides a novel therapeutic for obese patients with OSAHS, especially in patients with poor continuous positive air pressure (CPAP) adherence. To date, the resolution mechanism of OSAHS in obese patients after MBS has not been fully clarified. In addition, there is no specific metabolic bariatric surgical treatment of OSAHS guidelines. Therefore, this review provides an update on the relationship between OSAHS and MBS for highlighting the importance of weight loss strategies for obese patients with OSAHS.

摘要

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与肥胖密切相关,可导致多器官和系统损害。代谢减重手术(MBS)目前是唯一长期有效的治疗方法,也是肥胖人群的重要策略,也为肥胖合并 OSAHS 患者提供了新的治疗方法,尤其是 CPAP 依从性差的患者。迄今为止,肥胖患者 MBS 后 OSAHS 的缓解机制尚未完全阐明。此外,也没有针对 OSAHS 的具体代谢减重手术治疗指南。因此,本文就 OSAHS 与 MBS 的关系进行综述,强调了肥胖合并 OSAHS 患者的减重策略的重要性。

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