Department of Urology, Alexandria University, Alexandria, Egypt.
Department of Urology, Alexandria University, Alexandria, Egypt.
Urology. 2021 Mar;149:133-139. doi: 10.1016/j.urology.2020.12.019. Epub 2020 Dec 26.
To assess prognostic factors affecting successful low-intensity extracorporeal shockwave therapy (Li-ESWT) treatment of erectile dysfunction (ED) in patients with vasculogenic ED and to report 30-month follow-up.
This study was conducted upon 425 patients with vasculogenic ED. Assessment of ED was done using Sexual Health Inventory for Men (SHIM) score. Patients were treated by Li-ESWT using PiezoWave2 (Richard Wolf) device. Successful Li-ESWT was defined as 6-month SHIM score of 22-25. Patients with successful treatment were followed for 30 months.
Mean Baseline SHIM scores for the total population studied was 11.8 with a range from 5 to 20. After 6 months from treatment, 220 (51.8%) patients reported satisfactory sexual intercourse. Age, diabetes, hypertension, smoking, obesity, hyperlipidemia, pretreatment SHIM score, and the duration of ED were all found to be significant factors affecting the success of Li-ESWT. At 30-month follow-up, 168 (76.3%) patients from those who responded to Li-ESWT still reported satisfactory sexual intercourse with a SHIM score of 22-25 without using PDE5i.
Li-ESWT is safe and effective treatment of ED with 30 months success in 39.5% of patients treated. Li-ESWT should be offered to patients with mild-to-moderate ED and not to those with severe ED.
评估影响血管性勃起功能障碍（ED）患者低强度体外冲击波治疗（Li-ESWT）成功的预后因素，并报告 30 个月随访结果。
本研究纳入了 425 例血管性 ED 患者。采用男性性功能健康问卷（SHIM）评分评估 ED。使用 PiezoWave2（Richard Wolf）设备对患者进行 Li-ESWT 治疗。将 6 个月时 SHIM 评分达到 22-25 定义为 Li-ESWT 成功。成功治疗的患者随访 30 个月。
研究人群的平均基线 SHIM 评分为 11.8，范围为 5-20。治疗后 6 个月，220 例（51.8%）患者报告了满意的性生活。年龄、糖尿病、高血压、吸烟、肥胖、高脂血症、治疗前 SHIM 评分和 ED 持续时间均被发现是影响 Li-ESWT 成功的显著因素。在 30 个月随访时，168 例对 Li-ESWT 有反应的患者（76.3%）仍报告了满意的性生活，SHIM 评分为 22-25，且未使用 PDE5i。
Li-ESWT 是一种安全有效的 ED 治疗方法，治疗 30 个月后，39.5%的患者成功。Li-ESWT 应提供给轻度至中度 ED 患者，而不是严重 ED 患者。
