Department of Microbiology and Immunology, National University of Singapore, 21 Lower Kent Ridge Road, 119077, Singapore.
Duke-NUS Medical School, 8 College Road, 169857, Singapore.
Complement Ther Med. 2021 Mar;57:102652. doi: 10.1016/j.ctim.2020.102652. Epub 2020 Dec 26.
With the rise in complementary medicine usage, mind-body interventions (MBI), encompassing therapies like yoga and music therapy, have been gaining interest. The use of MBI in non-chronic kidney disease (CKD) patients have demonstrated efficacy for ameliorating pain, stress and anxiety symptoms. As CKD patients often suffer from these symptoms, MBI may serve as potential adjunctive therapies. This review aimed to summarize the studied indications of MBI among CKD patients.
A systematic review was performed in Medline®, Embase®, Scopus®, CINAHL®, CENTRAL® and PsycInfo® in accordance to the PRISMA and SWiM checklists. Randomised controlled trials (RCTs) which evaluated the use of MBI among adult CKD patients were included. The efficacy of each MBI was determined by reduction in symptoms severity scores. All adverse reactions were documented.
Of the 7,417 articles screened, 32 RCTs were included. Music therapy (n = 11), relaxation therapy (n = 9) and spiritual therapy (n = 6) were the most well studied MBIs. Frequently studied indications for MBIs were anxiety symptoms (n = 12), pain (n = 7) and depressive symptoms (n = 5). Music and spiritual therapies were shown to reduce 8.06-43.5 % and 36.1-41.1 % of anxiety symptoms respectively. For pain relief, music (41.8 %-61.5 %) and yoga therapies (36.7 %) were shown to be effective for reduction of pain. Lastly, spiritual therapy was shown to reduce depressive symptoms by 56.8 %. No adverse effects were reported for any MBI.
Music therapy, relaxation and spiritual therapies are more well-studied MBIs which were shown to reduce anxiety, depressive symptoms and pain in CKD patients. Larger RCTs are required to confirm the efficacy and safety of promising MBIs.
随着补充医学的使用增加，身心干预（MBI），包括瑜伽和音乐疗法等疗法，已引起关注。MBI 在非慢性肾脏病（CKD）患者中的应用已证明对缓解疼痛、压力和焦虑症状有效。由于 CKD 患者经常出现这些症状，MBI 可能是潜在的辅助治疗方法。本综述旨在总结 CKD 患者中 MBI 的研究适应症。
按照 PRISMA 和 SWiM 清单，在 Medline®、Embase®、Scopus®、CINAHL®、CENTRAL®和 PsycInfo®中进行系统评价。纳入评估成年 CKD 患者使用 MBI 的随机对照试验（RCT）。通过症状严重程度评分的降低来确定每种 MBI 的疗效。记录所有不良反应。
在筛选出的 7417 篇文章中，有 32 篇 RCT 被纳入。音乐疗法（n = 11）、放松疗法（n = 9）和精神疗法（n = 6）是研究最多的 MBI。MBI 经常研究的适应症包括焦虑症状（n = 12）、疼痛（n = 7）和抑郁症状（n = 5）。音乐和精神疗法分别显示可减少 8.06%-43.5%和 36.1%-41.1%的焦虑症状。在缓解疼痛方面，音乐（41.8%-61.5%）和瑜伽疗法（36.7%）被证明有效缓解疼痛。最后，精神疗法显示可减少 56.8%的抑郁症状。任何 MBI 均未报告不良反应。
音乐疗法、放松疗法和精神疗法是研究较多的 MBI，已证明可减轻 CKD 患者的焦虑、抑郁症状和疼痛。需要更大规模的 RCT 来确认有前途的 MBI 的疗效和安全性。
