Brun Claire, Exbrayat Jean-Marie, Raquet Michel
Sciences and Humanities Confluence Research Center, UCLy, CEDEX 02, 69288 Lyon, France.
Ecole Pratique des Hautes Etudes, Paris Sciences Lettres, CEDEX 02, 69288 Lyon, France.
Animals (Basel). 2020 Dec 22;11(1):2. doi: 10.3390/ani11010002.
Reproduction in vertebrates is controlled by the hypothalamo-pituitary-gonadal axis, and both the sex steroid and pituitary hormones play a pivotal role in the regulation of the physiology of the oviduct and events occurring within the oviduct. Their hormonal actions are mediated through interaction with specific receptors. Our aim was to locate α and β estrogen receptors, progesterone receptors, gonadotropin and prolactin receptors in the tissues of the oviduct of (Amphibia, Gymnophiona), in order to study the correlation between the morphological changes of the genital tract and the ovarian cycle. Immunohistochemical methods were used. We observed that sex steroids and pituitary hormones were involved in the morpho-functional regulation of oviduct, and that their cellular detection was dependent on the period of the reproductive cycle.
脊椎动物的生殖受下丘脑-垂体-性腺轴控制,性类固醇激素和垂体激素在输卵管生理调节以及输卵管内发生的事件中均起关键作用。它们的激素作用是通过与特定受体相互作用介导的。我们的目的是在蚓螈目(两栖纲)输卵管组织中定位α和β雌激素受体、孕激素受体、促性腺激素和催乳素受体,以研究生殖道形态变化与卵巢周期之间的相关性。采用了免疫组织化学方法。我们观察到性类固醇激素和垂体激素参与了输卵管的形态功能调节,并且它们在细胞中的检测取决于生殖周期的阶段。