临床医师对低体温的识别不足，与感染性危重症患者的死亡率升高相关：一项回顾性观察研究。

Hypothermia, Poorly Recognized by clinicians, is associated with Higher Mortality Among Critically Ill Patients with infections: A Retrospective Observational Study.

机构信息

Research Institute for Radiation Biology and Medicine, Department of Radiation Disaster Medicine, Hiroshima University, Hiroshima, Japan; Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Clinical Training Resident, Hiroshima University Hospital, Hiroshima, Japan.

出版信息

J Infect Chemother. 2021 Mar;27(3):540-543. doi: 10.1016/j.jiac.2020.12.016. Epub 2020 Dec 26.

DOI:10.1016/j.jiac.2020.12.016

PMID:33376031

Abstract

We investigated the relationship between the presence of hypothermia in infection and mortality in 233 infectious critically ill patients. The adjusted hazard ratio for death at 28 days in the low body temperature group was 3.30 compared with the high body temperature group. The proportion of appropriate antimicrobial therapy significantly decreased with decreasing body temperature. The proportion of medical records that documented body temperature abnormality in the low body temperature group (33%) was significantly lower than that in the high body temperature group (69%). Delayed antimicrobial therapy in patients with hypothermia, which may be due to poor recognition by physicians, could result in mortality.

摘要

我们调查了 233 例感染性危重症患者中感染性低体温与死亡率之间的关系。与高热组相比，低温组 28 天死亡的调整危险比为 3.30。随着体温的降低，适当的抗菌治疗比例显著下降。在低温组中，记录体温异常的病历比例（33%）明显低于高热组（69%）。低温患者抗菌治疗延迟，这可能是由于医生识别能力较差所致，可能导致死亡率增加。