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抗凝血酶III缺乏所致的肠系膜静脉血栓形成

Mesenteric venous thrombosis due to antithrombin III deficiency.

作者信息

Maung R, Kelly J K, Schneider M P, Poon M C

机构信息

Department of Pathology, University of Calgary, Faculty of Medicine, Alberta, Canada.

出版信息

Arch Pathol Lab Med. 1988 Jan;112(1):37-9.

PMID:3337617
Abstract

A 19-year-old woman developed gradually worsening abdominal pain, signs of peritonitis, and hematemesis. Laparotomy revealed peritonitis due to segmental small-bowel infarction, and the underlying pathologic condition was mesenteric vein thrombosis. A primary thrombotic disorder was suggested and antithrombin III deficiency was found. Before anticoagulant therapy could be initiated, she developed hemorrhagic cerebral infarction and died. Her history included three episodes of deep vein thrombosis while taking oral contraceptives. Her father died of spontaneous mesenteric and portal vein thrombosis at age 29 years. This report underlines the importance of careful interpretation of the vascular pathology in cases of intestinal ischemia.

摘要

一名19岁女性出现腹痛逐渐加重、腹膜炎体征和呕血。剖腹探查显示为节段性小肠梗死所致腹膜炎,潜在病理状况为肠系膜静脉血栓形成。提示存在原发性血栓形成障碍,且发现抗凝血酶III缺乏。在开始抗凝治疗前,她发生了出血性脑梗死并死亡。她的病史包括在服用口服避孕药期间发生过3次深静脉血栓形成。她的父亲在29岁时死于自发性肠系膜和门静脉血栓形成。本报告强调了在肠道缺血病例中仔细解读血管病理的重要性。

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1
Mesenteric venous thrombosis due to antithrombin III deficiency.抗凝血酶III缺乏所致的肠系膜静脉血栓形成
Arch Pathol Lab Med. 1988 Jan;112(1):37-9.
2
Antithrombin III deficiency appearing as mesenteric vein thrombosis.表现为肠系膜静脉血栓形成的抗凝血酶III缺乏症
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Intimal hyperplasia and thrombosis of the visceral arteries in a young woman: possible relation with oral contraceptives and smoking.一名年轻女性内脏动脉的内膜增生和血栓形成:可能与口服避孕药及吸烟有关。
Surgery. 1988 Jun;103(6):706-10.
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[Segmental short bowel stenosis after a superior mesenteric vein thrombosis. Report of a case].[肠系膜上静脉血栓形成后节段性短肠狭窄。病例报告]
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Infarction of the midgut associated with oral contraceptives. Report of two cases.与口服避孕药相关的中肠梗死。两例报告。
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[Mesenteric vein thrombosis with hemorrhagic infarct of the small intestinal as a complication of oral contraceptives].
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[Mesenteric vein infarction associated with congenital antithrombin III (ATIII) deficiency].[与先天性抗凝血酶III(ATIII)缺乏相关的肠系膜静脉梗死]
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[Spontaneous mesenteric venous thrombosis, a rare complication of oral contraceptives (author's transl)].
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