Dong Haoran, Liu Shuang, Jing Li, Tian Mengyuan, Sun Jinglun, Pang Yanmin, Xing Liying, Xu Yingying
Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China (mainland).
Department of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China (mainland).
Med Sci Monit. 2020 Dec 30;26:e926581. doi: 10.12659/MSM.926581.
BACKGROUND We aimed to profile the current epidemiology of hypertension among the survivors of hemorrhagic stroke in northeast China. MATERIAL AND METHODS Our cross-sectional study included 18 796 adults aged 40 years or older and residing in northeast China. Hemorrhagic stroke was identified according to the CT and/or MRI results. Hypertension was defined based on the Chinese hypertension guidelines. RESULTS We identified 208 patients with previous hemorrhagic stroke in this population-based study. The overall prevalence of hypertension in the studied population was 88%. Out of all the survivors of hemorrhagic stroke, 80.9% were aware of their hypertensive condition, 70.5% of the patients were in antihypertensive medications treatment, and only 12% of the patients had their blood pressure under control. Furthermore, only 17.10% of the patients who took hypertensive medications achieved appropriate blood pressure. Calcium channel blockers were more commonly used than other medications. Patients with controlled hypertension had significantly higher percentages of comorbidities when compared to those with uncontrolled hypertension. In our patient sample, the rates of stage 2 and stage 3 hypertension in the hemorrhagic stroke population were 28.8% and 15.9%, respectively, and women had a significantly higher prevalence of stage 3 hypertension when compared with men (21.3% vs. 10.0%, P=0.026). CONCLUSIONS The high prevalence of uncontrolled hypertension and high rates of blood pressure at stages 2 and 3 in patients with prior hemorrhagic stroke indicated a considerable stroke burden in northeast China. Therefore, effective and long-time management of hypertension in stroke survivors should be a priority.
背景 我们旨在剖析中国东北地区出血性卒中幸存者中高血压的当前流行病学情况。
材料与方法 我们的横断面研究纳入了18796名年龄在40岁及以上且居住在中国东北地区的成年人。根据CT和/或MRI结果确定出血性卒中。高血压依据中国高血压指南进行定义。
结果 在这项基于人群的研究中，我们识别出208例既往有出血性卒中的患者。研究人群中高血压的总体患病率为88%。在所有出血性卒中幸存者中，80.9%知晓自己患有高血压，70.5%的患者接受抗高血压药物治疗，而只有12%的患者血压得到控制。此外，在服用抗高血压药物的患者中，只有17.10%的患者血压控制得当。钙通道阻滞剂比其他药物更常用。与血压未得到控制的患者相比，血压得到控制的患者合并症的比例显著更高。在我们的患者样本中，出血性卒中人群中2级和3级高血压的发生率分别为28.8%和15.9%，女性3级高血压的患病率显著高于男性（21.3%对10.0%，P = 0.026）。
结论 既往有出血性卒中的患者中，未控制的高血压患病率高以及2级和3级高血压发生率高，表明中国东北地区存在相当大的卒中负担。因此，对卒中幸存者进行有效且长期的高血压管理应成为优先事项。
