Swart Eric, Adair Chris, Seymour Rachel B, Karunakar Madhav A
Department of Orthopedics and Physical Rehabilitation, University of Massachusetts, Worcester, MA USA.
Department of Orthopedic Surgery, Atrium Health Musculoskeletal Institute, 1025 Morehead Medical Plaza, Suite 300, Charlotte, NC 28204 USA.
HSS J. 2020 Dec;16(Suppl 2):378-382. doi: 10.1007/s11420-020-09762-8. Epub 2020 Jun 8.
Osteoporotic hip fractures typically occur in frail elderly patients with multiple comorbidities, and repair of the fracture within 48 h is recommended. Pre-operative evaluation sometimes involves transthoracic echocardiography (TTE) to screen for heart disease that would alter peri-operative management, yet TTE can delay surgery and is resource intensive. Evidence suggests that the use of clinical practice guidelines (CPGs) can improve care. It is unclear which guidelines are most useful in hip fracture patients.
QUESTIONS/PURPOSES: We sought to evaluate the performance of the five commonly used CPGs in determining which patients with acute fragility hip fracture require TTE and to identify common features among high-performing CPGs that could be incorporated into care pathways.
We performed a retrospective study of medical records taken from an institutional database of osteoporotic hip fracture patients to identify those who underwent pre-operative TTE. History and physical examination findings were recorded; listed indications for TTE were compared against those given in five commonly used CPGs: those from the American College of Cardiology/American Heart Association (ACC/AHA), the British Society of Echocardiography (BSE), the European Society of Cardiology and the European Society of Anaesthesiology(ESC/ESA), the Association of Anaesthetists of Great Britain and Ireland (AAGBI), and the Scottish Intercollegiate Guidelines Network (SIGN). We then calculated the performance (sensitivity and specificity) of the CPGs in identifying patients with TTE results that had the potential to change peri-operative management.
We identified 100 patients who underwent pre-operative TTE. Among those, the patients met criteria for TTE 32 to 66% of the time, depending on the CPG used. In 14% of those receiving TTE, the test revealed new information with the potential to change management. The sensitivity of the CPGs ranged from 71% (ESC/ESA and AAGBI) to 100% (ACC/AHA and SIGN). The CPGs' specificity ranged from 37% (BSE) to 74% (ESC/ESA). The more sensitive guidelines focused on a change in clinical status in patients with known disease or clinical concern regarding new-onset disease.
In patients requiring fixation of osteoporotic hip fractures, TTE can be useful for identifying pathologies that could directly change peri-operative management. Our data suggest that established CPGs can be safely used to identify which patients should undergo pre-operative TTE with low risk of missed pathology.
骨质疏松性髋部骨折通常发生在患有多种合并症的体弱老年患者中,建议在48小时内进行骨折修复。术前评估有时需要进行经胸超声心动图(TTE)检查,以筛查可能改变围手术期管理的心脏病,但TTE可能会延迟手术且资源消耗大。有证据表明,使用临床实践指南(CPG)可以改善护理。目前尚不清楚哪些指南对髋部骨折患者最有用。
问题/目的:我们试图评估五种常用CPG在确定哪些急性脆性髋部骨折患者需要TTE方面的性能,并确定高性能CPG中可纳入护理路径的共同特征。
我们对取自骨质疏松性髋部骨折患者机构数据库的病历进行了回顾性研究,以确定那些接受术前TTE检查的患者。记录病史和体格检查结果;将列出的TTE适应症与五种常用CPG中的适应症进行比较:美国心脏病学会/美国心脏协会(ACC/AHA)、英国超声心动图学会(BSE)、欧洲心脏病学会和欧洲麻醉学会(ESC/ESA)、大不列颠及爱尔兰麻醉医师协会(AAGBI)以及苏格兰校际指南网络(SIGN)。然后,我们计算了CPG在识别TTE结果可能改变围手术期管理的患者方面的性能(敏感性和特异性)。
我们确定了100例接受术前TTE检查的患者。其中,根据所使用的CPG,患者符合TTE标准的时间为32%至66%。在接受TTE检查的患者中,14%的检查发现了可能改变管理的新信息。CPG的敏感性范围为71%(ESC/ESA和AAGBI)至100%(ACC/AHA和SIGN)。CPG的特异性范围为37%(BSE)至74%(ESC/ESA)。更敏感的指南侧重于已知疾病患者临床状态的变化或对新发疾病的临床关注。
在需要固定骨质疏松性髋部骨折的患者中,TTE有助于识别可能直接改变围手术期管理的病变。我们的数据表明,既定的CPG可安全用于识别哪些患者应接受术前TTE检查,漏诊病变的风险较低。