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微创外科手术治疗胃胃肠间质瘤——单中心经验。

Minimal Access Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumours - A Single Centre Experience.

出版信息

Chirurgia (Bucur). 2020 Nov-Dec;115(6):726-734. doi: 10.21614/chirurgia.115.6.726.

Abstract

Laparoscopic techniques have been increasingly adopted in the field of General Surgery in the last decades. The main disadvantages of laparoscopy are related to limited degrees of freedom of instruments and poor ergonomics, which are associated with a steep learning curve. Robotic surgery overcomes most of the technical limitations of laparoscopic surgery and has the potential to expand the indications of minimal access surgery (MAS) in procedures that are difficult to perform using laparoscopy. Patients who underwent MAS resections of gastric gastrointestinal stromal tumours (GIST) between January 2002 and October 2018 in a single Surgical Department were retrospectively analysed. Demographic data as well as the following characteristics were recorded for each patient: age, sex, symptoms, tumour location and size, type of surgical procedure, intraoperative blood loss, operative time, length of hospital stay, histopathological assessment of resection margins, and incidence of perioperative complications. The mean patient age was 58 (range, 27-81 years). Most lesions were found on the great curvature (7) and in the distal stomach or antrum (7), respectively. Twenty patients underwent laparoscopic resection, while five patients had robotic resection of gastric GISTs. Surgical laparoscopic treatment consisted of antrectomy (n=4) and wedge gastrectomy (n=16). In all robotic cases a wedge gastrectomy was performed. One patient was converted to open surgery due to adhesions from previous operation. The mean operative time was 130 minutes (range, 70-210 minutes).The mean tumour size was 3.8 cm (range, 2-7 cm). There were no complications except one case that required reoperation for postoperative bleeding. There were no mortalities. Conclusion: The MAS approach of gastric GISTs is safe and effective and it is associated with low morbidity. Therefore, it should constitute the first option in patients with small tumours and favourable locations. The only limiting factor for the widespread use of MAS resections for gastric GISTs is surgeon expertise in this challenging technique.

摘要

在过去的几十年中,腹腔镜技术在普通外科领域得到了越来越多的应用。腹腔镜的主要缺点与仪器的自由度有限和人机工程学不佳有关,这与陡峭的学习曲线有关。机器人手术克服了腹腔镜手术的大多数技术限制,并有可能扩大微创外科手术(MAS)在使用腹腔镜难以进行的手术中的适应证。

回顾性分析了 2002 年 1 月至 2018 年 10 月期间在一个外科部门接受 MAS 胃胃肠间质瘤(GIST)切除术的患者。记录了每位患者的人口统计学数据以及以下特征:年龄、性别、症状、肿瘤位置和大小、手术类型、术中失血量、手术时间、住院时间、切除边缘的组织病理学评估以及围手术期并发症的发生率。

患者的平均年龄为 58 岁(范围为 27-81 岁)。大多数病变位于大曲率(7 个)和胃远端或胃窦(7 个)。20 例患者接受腹腔镜切除术,5 例患者接受机器人胃 GIST 切除术。手术腹腔镜治疗包括胃切除术(n=4)和楔形胃切除术(n=16)。在所有机器人病例中,均进行了楔形胃切除术。由于先前手术的粘连,1 例患者转为开放性手术。手术时间平均为 130 分钟(范围为 70-210 分钟)。肿瘤平均大小为 3.8 厘米(范围为 2-7 厘米)。除 1 例术后出血需要再次手术的并发症外,无其他并发症。无死亡病例。结论:MAS 方法治疗胃 GIST 是安全有效的,且发病率低。因此,对于肿瘤较小且位置良好的患者,应作为首选。MAS 胃 GIST 切除术广泛应用的唯一限制因素是外科医生在这项具有挑战性的技术方面的专业知识。

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