Král Zdeněk, Adam Zdeněk, Ježová Marta, Pour Luděk, Krejčí Marta
Vnitr Lek. 2020 Summer;66(6):19-27.
The histiocytoses are rare disorders characterized by the accumulation of cells thought to be derived from dendritic cells or macrophages. Their clinical behaviour ranges from mild to disseminated and, sometimes, life-threatening forms. The incidence of this diseases is much smaller, then the incidence of diseases derived from lymphocytic or myeloid lineage. Langerhans cell histiocytosis is most frequent disease from this group. The last version of WHO classification from 2017 and last version of classification published by Histiocyte Society is summarised in this paper.
组织细胞增多症是一类罕见的疾病，其特征是细胞积聚，这些细胞被认为源自树突状细胞或巨噬细胞。它们的临床行为从轻度到播散性，有时甚至是危及生命的形式。这类疾病的发病率远低于源自淋巴细胞或髓系谱系的疾病。朗格汉斯细胞组织细胞增多症是该组中最常见的疾病。本文总结了2017年世界卫生组织分类的最新版本以及组织细胞协会发布的分类的最新版本。
