瑞典农民呼吸器官中的癌症。

Cancer in the respiratory organs of Swedish farmers.

作者信息

Wiklund K, Steineck G

机构信息

Department of Cancer Epidemiology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.

出版信息

Cancer. 1988 Mar 1;61(5):1055-8. doi: 10.1002/1097-0142(19880301)61:5<1055::aid-cncr2820610534>3.0.co;2-u.

DOI:10.1002/1097-0142(19880301)61:5<1055::aid-cncr2820610534>3.0.co;2-u

PMID:3338050

Abstract

In a cohort of 254,417 male Swedish farmers (4,330,717 person-years) the incidence of cancer of the respiratory organs was compared to a reference cohort of 1,725,845 men (30,131,664 person-years) employed in other economic activities than agriculture or forestry. In the study cohort 1450 cases of cancer in the respiratory organs were found in 1961 to 1979 resulting in an estimated relative risk (RR) of 0.38 (95% confidence interval [CI]: 0.36-0.40). For cancer of trachea, bronchus and lung, the decreased risk was equal for adenocarcinoma and squamous cell carcinoma. No time related trend in RR for any of the histologic subtypes could be seen. However, for squamous cell carcinoma in nose and nasal sinuses RR has increased from 0.42 (95% CI: 0.20-0.80) in 1961 to 1966 to 2.06 (95% CI: 1.22-3.50) in 1974 to 1979.

摘要

在一个由254417名瑞典男性农民组成的队列（4330717人年）中，将呼吸器官癌症的发病率与一个由1725845名从事农业或林业以外其他经济活动的男性组成的参照队列（30131664人年）进行了比较。在研究队列中，1961年至1979年期间发现了1450例呼吸器官癌症病例，估计相对风险（RR）为0.38（95%置信区间[CI]：0.36 - 0.40）。对于气管、支气管和肺癌，腺癌和鳞状细胞癌的风险降低程度相同。未观察到任何组织学亚型的RR随时间的相关趋势。然而，对于鼻和鼻窦的鳞状细胞癌，RR已从1961年至1966年的0.42（95% CI：0.20 - 0.80）增加到1974年至1979年的2.06（95% CI：1.22 - 3.50）。