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对于合适的患者,髋关节表面置换术的益处有哪些?一项回顾性倾向评分匹配分析。

What Are the Benefits of Hip Resurfacing in Appropriate Patients? A Retrospective, Propensity Score-Matched Analysis.

作者信息

McLawhorn Alexander S, Buller Leonard T, Blevins Jason L, Lee Yuo Yu, Su Edwin P

机构信息

Division of Adult Reconstruction and Joint Replacement, Department of Orthopedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021 USA.

Department of Orthopaedic Surgery, Indiana University School of Medicine, 340 W 10th St #6200, Indianapolis, IN 46202 USA.

出版信息

HSS J. 2020 Dec;16(Suppl 2):316-326. doi: 10.1007/s11420-019-09729-4. Epub 2019 Dec 4.

Abstract

BACKGROUND

Hip arthritis is one of the major causes of disability worldwide. Hip resurfacing arthroplasty (HRA) has emerged in recent years as an alternative to total hip arthroplasty (THA), but complications of HRA have limited the patient population to younger male patients with primary osteoarthritis and large hip anatomy. How the functional benefits of HRA in this population compare with those of THA is not entirely clear.

QUESTIONS/PURPOSES: The primary aim of this study was to determine whether there were differences in hip disability and patient satisfaction with surgery between these two groups at 2 years after surgery, using patient-reported outcome measures (PROMs) and subjective measures of patient satisfaction. Additionally, we sought to determine whether there were differences in post-operative discharge disposition, revision rates, or adverse events.

METHODS

We searched an institutional database to identify patients undergoing unilateral HRA or THA between January 2007 and July 2011 who met today's recommended criteria for HRA: younger male patients with large-enough hip anatomy to make surgery viable (a femoral head of at least 48 mm in HRA patients and, in THA patients, an acetabular shell size of 54 mm, the minimum outer shell size that could accommodate a femoral head component of 48 mm; for matching purposes, acetabular shell size in THA was used as a surrogate for the femoral head size used in HRA). We used propensity score matching to control for potentially confounding pre-operative variables and administered the Hip Disability and Osteoarthritis Outcome Score (HOOS) survey, including its subdomains, at the 2-year mark. We also assessed differences between groups in Lower Extremity Activity Scale scores, 12-item Short Form Health Survey results, and answers regarding satisfaction with surgery. We calculated minimal detectable change, minimum clinically important change, and substantial clinical benefit using anchor-based techniques for multiple outcome measures.

RESULTS

There were 251 patients in each group. HRA patients scored significantly higher than THA patients on the 2-year HOOS sports and recreation (92 versus 87, respectively) and on rates of overall satisfaction (94% versus 89%, respectively). The HRA group also had a greater chance of achieving minimum clinically important change (18.75 points) in the HOOS sports and recreation subdomains than the THA group (97% versus 91%). No significant difference was found in 6-month adverse event rates. HRA patients also had a significantly shorter mean hospital stay, a higher rate of discharge to home, and a lower incidence of a "significant" limp after surgery.

CONCLUSION

HRA may provide a functional benefit in sports and recreation and greater satisfaction in patients who meet the current criteria for HRA. Because these benefits may be small, pre-operative counseling should focus on balancing the possible functional benefits against the longer-term risks associated with metal-on-metal bearings.

摘要

背景

髋关节关节炎是全球致残的主要原因之一。髋关节表面置换术(HRA)近年来已成为全髋关节置换术(THA)的替代方法,但HRA的并发症将患者群体限制为患有原发性骨关节炎且髋关节解剖结构较大的年轻男性患者。HRA在该人群中的功能益处与THA相比究竟如何尚不完全清楚。

问题/目的:本研究的主要目的是使用患者报告结局测量指标(PROMs)和患者满意度主观测量指标,确定这两组患者术后2年时在髋关节功能障碍和手术患者满意度方面是否存在差异。此外,我们试图确定术后出院处置、翻修率或不良事件方面是否存在差异。

方法

我们检索了一个机构数据库,以识别2007年1月至2011年7月期间接受单侧HRA或THA手术且符合当今HRA推荐标准的患者:髋关节解剖结构足够大以使手术可行的年轻男性患者(HRA患者的股骨头至少48毫米,THA患者的髋臼杯尺寸为54毫米,这是可容纳48毫米股骨头组件的最小外壳尺寸;为进行匹配,THA中的髋臼杯尺寸用作HRA中使用的股骨头尺寸的替代指标)。我们使用倾向得分匹配来控制潜在的术前混杂变量,并在2年时进行髋关节功能障碍和骨关节炎结局评分(HOOS)调查,包括其各个子领域。我们还评估了两组在下肢活动量表评分、12项简短健康调查问卷结果以及手术满意度回答方面的差异。我们使用基于锚定的技术对多种结局测量指标计算最小可检测变化、最小临床重要变化和实质性临床益处。

结果

每组有251名患者。HRA组患者在2年的HOOS运动与娱乐方面得分显著高于THA组患者(分别为92分和87分),总体满意度也更高(分别为94%和89%)。HRA组在HOOS运动与娱乐子领域实现最小临床重要变化(18.75分)的可能性也高于THA组(97%对91%)。6个月不良事件发生率未发现显著差异。HRA组患者的平均住院时间也显著更短,回家出院率更高,术后“明显”跛行的发生率更低。

结论

对于符合当前HRA标准的患者,HRA可能在运动与娱乐方面提供功能益处,并带来更高的满意度。由于这些益处可能较小,术前咨询应侧重于权衡可能的功能益处与金属对金属轴承相关的长期风险。

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