Buyukavci Raikan, Akturk Semra, Evren Bahri, Ersoy Yuksel
Department of Physical Medicine and Rehabilitation, Inonu University Faculty of Medicine, Malatya, Turkey.
Department of Endocrinology, Inonu University Faculty of Medicine, Malatya, Turkey.
North Clin Istanb. 2020 Oct 1;7(6):585-590. doi: 10.14744/nci.2020.28003. eCollection 2020.
Combined osteopenia/osteoporosis and sarcopenia is a major public health problem for old adults. In this study, we aimed to evaluate the impacts of combined osteopenia/osteoporosis with sarcopenia on balance and quality of life in patients older than 65 years.
In this sudy, 77 patients with sarcopenia, who were older than 65 years, were included. The diagnosis of sarcopenia was made according to the diagnostic criteria developed by The European Working Group on Sarcopenia in Older People (EWGSOP). Bone densitometry was performed to screen for osteoporosis or osteopenia. The balance was assessed with the anterior-posterior stability index (APSI), medial-lateral stability index (MLSI), and the general stability index (OSI), which were calculated using a Biodex Stability System device (BSS). The quality of life was assessed using SF-36.
Patients with sarcopenia were included in this study. Of them, 40 had osteoporosis and 37 had osteopenia. The measures of balance and the OSI, APSI, and MLSI values were low in both groups of patients, but they were statistically significantly lower in the sarcopenia with osteoporosis group compared to the sarcopenia with osteopenia group (p=0.01; p=0.002; p=0.04, respectively). The quality of life was lower in all sub-categories of SF-36, excluding the mental health when sarcopenia was accompanied by osteoporosis compared to the joint occurrence of sarcopenia with osteopenia (p<0.05).
Our study suggests that the joint occurrence of osteoporosis with sarcopenia is associated with a risk of balance loss, a decrease in quality of life, and a potentially increased fracture risk in older adults.
骨质减少/骨质疏松与肌肉减少症并存是老年人面临的一个重大公共卫生问题。在本研究中，我们旨在评估骨质减少/骨质疏松合并肌肉减少症对65岁以上患者平衡能力和生活质量的影响。
本研究纳入了77例年龄大于65岁的肌肉减少症患者。根据欧洲老年人肌肉减少症工作组（EWGSOP）制定的诊断标准进行肌肉减少症的诊断。进行骨密度测量以筛查骨质疏松症或骨质减少症。使用Biodex稳定性系统设备（BSS）计算前后稳定性指数（APSI）、内外侧稳定性指数（MLSI）和总体稳定性指数（OSI）来评估平衡能力。使用SF-36评估生活质量。
本研究纳入了肌肉减少症患者。其中，40例患有骨质疏松症，37例患有骨质减少症。两组患者的平衡能力测量值以及OSI、APSI和MLSI值均较低，但与骨质减少合并肌肉减少症组相比，骨质疏松合并肌肉减少症组的这些值在统计学上显著更低（分别为p = 0.01；p = 0.002；p = 0.04）。与骨质减少合并肌肉减少症同时出现相比，当肌肉减少症伴有骨质疏松症时，SF-36所有子类别中的生活质量均较低，但心理健康类别除外（p < 0.05）。
我们的研究表明，骨质疏松症与肌肉减少症并存与老年人平衡能力丧失风险、生活质量下降以及潜在的骨折风险增加有关。
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