Lee Do-Youn, Shin Sunghoon
Research Institute of Human Ecology, Yeungnam University, Gyeongsan-si 38541, Gyungbuk, Korea.
Neuromuscular Control Laboratory, Yeungnam University, Gyeongsan-si 38541, Gyeongbuk, Korea.
J Clin Med. 2021 Dec 27;11(1):129. doi: 10.3390/jcm11010129.
Sarcopenia and bone disorders, such as osteopenia and osteoporosis, are common musculoskeletal disorders in older adults. Therefore, this study aimed to establish the association between sarcopenia and bone disorders such as osteoporosis and osteopenia according to sex. We analyzed 3077 participants from the 2008-2011 Korean National Health and Nutrition Examination Survey aged 65 years or older. After adjusting for all covariates, such as physical examinations, exercise, and nutrient intake (model 4), the odds ratios for the association between sarcopenia and bone disorders were 2.051 (95% confidence interval [CI]: 1.498-2.808) in osteopenia and 2.258 (95% CI: 1.584-3.218) in osteoporosis. However, when sex was analyzed separately, the odds ratio was significantly different in men (osteopenia-2.068, 95% CI: 1.462-2.924; osteoporosis-3.247, 95% CI: 1.953-5.399), but not in women. Therefore, the results of this study show an association between sarcopenia and bone disorders in older Korean adults. Sarcopenia is significantly related to osteopenia and osteoporosis, especially in men, when stratified by sex.
肌肉减少症与骨质减少和骨质疏松等骨骼疾病是老年人常见的肌肉骨骼疾病。因此，本研究旨在根据性别确定肌肉减少症与骨质疏松和骨质减少等骨骼疾病之间的关联。我们分析了2008 - 2011年韩国国家健康与营养检查调查中3077名65岁及以上的参与者。在对所有协变量进行调整后，如体格检查、运动和营养摄入（模型4），肌肉减少症与骨质减少之间关联的优势比为2.051（95%置信区间[CI]：1.498 - 2.808），与骨质疏松之间关联的优势比为2.258（95% CI：1.584 - 3.218）。然而，当按性别分别分析时，男性的优势比有显著差异（骨质减少 - 2.068，95% CI：1.462 - 2.924；骨质疏松 - 3.247，95% CI：1.953 - 5.399），而女性则无显著差异。因此，本研究结果表明韩国老年成年人中肌肉减少症与骨骼疾病之间存在关联。按性别分层时，肌肉减少症与骨质减少和骨质疏松显著相关，尤其是在男性中。
