Schneider J, Erasun F, Hervas J L, Acinas O, Gonzalez-Rodilla I
Department of Obstetrics and Gynecology, Hospital Nacional Valdecilla, Santander, Spain.
Gynecol Oncol. 1988 Feb;29(2):245-9. doi: 10.1016/0090-8258(88)90220-x.
A 27-year-old woman with grade 3 immature teratoma of the ovary was treated with unilateral salpingo-oophorectomy and VAC combination chemotherapy. She received 6 postoperative courses, although initially 12 were planned. Chemotherapy had to be discontinued because of severe bone marrow toxicity. Eighteen months later the patient became pregnant and was ultimately delivered of a normal child. This is the second report of a successful pregnancy following VAC chemotherapy for immature teratoma.