脆性X染色体中三射和多射构型的频率。
Frequency of tri- and multiradial configurations in fragile X chromosomes.
作者信息
Subrt I, Stirská K
机构信息
Institute for the Care of Mother and Child, Prague, Czechoslovakia.
出版信息
Hum Genet. 1988 Feb;78(2):196-7. doi: 10.1007/BF00278198.
PMID:3338804
Abstract
The appearance of tri- or multiradial configurations in fragile chromosomes is affected by the number of cell cycles in the folate antagonist system. In this study the lymphocytes were incubated for 96 h in a medium 199 without calf serum, and tri- or multiradial configurations were observed in 6 of 12 cases of fra(X) chromosome. The frequency ranged from 0.6% to 7.4% of fra(X) chromosomes.
摘要
脆性染色体中三辐射或多辐射构型的出现受叶酸拮抗剂系统中细胞周期数量的影响。在本研究中，淋巴细胞在不含小牛血清的199培养基中孵育96小时，在12例脆性X染色体（fra(X)）病例中的6例中观察到了三辐射或多辐射构型。其频率在fra(X)染色体的0.6%至7.4%之间。
Zotero 插件