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聚乙二醇酸网预防胸腔镜肺大疱切除术复发。

Polyglycolic acid mesh for preventing post-thoracoscopic bullectomy recurrence.

机构信息

Department of Thoracic Surgery, Yoshijima Hospital, 3-2-33, Yoshijima-higashi, Naka-ku, Hiroshima, 730-0822, Japan.

Department of Surgery, Tsuchiya General Hospital, 3-30, Nakajima-cho, Naka-ku, Hiroshima, 730-8655, Japan.

出版信息

Surg Today. 2021 Jun;51(6):971-977. doi: 10.1007/s00595-020-02191-4. Epub 2021 Jan 2.

DOI:10.1007/s00595-020-02191-4
PMID:33389173
Abstract

PURPOSE

Thoracoscopic bullectomy is a common treatment modality for spontaneous pneumothorax but can result in a high frequency of postoperative recurrent pneumothorax in young patients. This retrospective study compared the recurrence rate of pneumothorax following conventional thoracoscopic bullectomy to that following bullectomy using a low-density polyglycolic acid mesh to cover the staple line.

METHODS

Group A comprised 237 patients who experienced 294 episodes of pneumothorax and underwent thoracoscopic bullectomy alone, and Group B comprised 130 patients who experienced 155 episodes of pneumothorax and underwent bullectomy with polyglycolic acid mesh used to cover the visceral pleura. To compare the postoperative inflammatory response between the two groups, we measured three inflammatory parameters: highest body temperature after surgery, C-reactive protein level on postoperative day 3, and change in eosinophil count from the day before the surgery to postoperative day 3.

RESULTS

The recurrence rate was significantly lower in Group B than in Group A (2.6% vs. 24.8%, P < 0.000001). All three inflammatory parameters were significantly higher in Group B than in Group A.

CONCLUSIONS

Using a polyglycolic acid mesh covering after thoracoscopic bullectomy resulted in acceptable long-term results (recurrence rate: 2.6%). This method was associated with a slightly elevated inflammatory response.

摘要

目的

胸腔镜肺大疱切除术是治疗自发性气胸的常用方法,但在年轻患者中可导致术后气胸复发率较高。本回顾性研究比较了传统胸腔镜肺大疱切除术后与使用低密度聚乙二醇酸网覆盖钉合线后肺大疱切除术后气胸复发率。

方法

A 组包括 237 例患者,共发生 294 次气胸,行单纯胸腔镜肺大疱切除术;B 组包括 130 例患者,共发生 155 次气胸,行肺大疱切除加聚乙二醇酸网覆盖脏层胸膜。为了比较两组术后炎症反应,我们测量了三个炎症参数:术后最高体温、术后第 3 天 C 反应蛋白水平和手术前一天到术后第 3 天嗜酸性粒细胞计数的变化。

结果

B 组的复发率明显低于 A 组(2.6%比 24.8%,P<0.000001)。B 组的所有三个炎症参数均明显高于 A 组。

结论

胸腔镜肺大疱切除术后使用聚乙二醇酸网覆盖可获得可接受的长期结果(复发率:2.6%)。这种方法与轻微升高的炎症反应相关。

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