Department of Orthopedics, Peking University Third Hospital, 49 North Garden Road, Beijing, 100191, China.
Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, 49 North Garden Road, Beijing, 100191, China.
Eur Spine J. 2021 Aug;30(8):2211-2220. doi: 10.1007/s00586-020-06688-x. Epub 2021 Jan 3.
To analyze the clinical and radiographic characteristics of thoracic disk disease associated with myelopathy (TDM).
This is a retrospective clinical review of prospectively collected imaging data based at a single institute. Based on preoperative CT and MRI, we classified TDM as thoracic disk herniation (TDH), THD with ossification (THDO), TDH with posterior bony avulsions of the vertebrae (TDH with PBA), TDH with posterior vertebral osteophytes (TDH with PVO), giant thoracic osteophyte and calcific discitis with herniation (CDH). Patient characteristics and radiographic data were compared between different types of TDM.
Among the 257 patients included, 12.06% of patients presented with symptoms after traumatic events. The most frequent complaint at onset and preoperative was back pain (29.2%) and subjective lower limb weakness (75.5%), respectively. All TDH with PBA is distributed at the lower thoracic segments, while CDH predominantly in the middle and lower thoracic segments. TDH with PBA was more frequent in men than TDH and CDH. Compared with TDH, TDHO, and TDH with PVO, TDH with PBA was younger in surgery age, and TDH and CDH had lower preoperative JOA scores than TDH with PBA. CDH had a larger ventral occupying ratio than TDH, TDHO, and TDH with PBA.
The onset of TDM was generally insidious but may be triggered acutely by apparently trivial events. With a low prevalence, TDM varied clinical symptoms. Different types of TDM had various clinical features, which might indicate different pathological mechanisms.
分析与脊髓病相关的胸椎间盘疾病(TDM)的临床和影像学特征。
这是一项基于单一机构前瞻性收集影像学数据的回顾性临床研究。根据术前 CT 和 MRI,我们将 TDM 分为胸椎间盘突出症(TDH)、伴有骨化的 THD(THDO)、伴有椎体后骨撕脱的 TDH(TDH 伴 PBA)、伴有椎体后骨赘的 TDH(TDH 伴 PVO)、巨大胸椎间盘骨赘和钙化性椎间盘炎伴突出(CDH)。比较不同类型 TDM 之间的患者特征和影像学数据。
在纳入的 257 名患者中,12.06%的患者在创伤事件后出现症状。最常见的首发和术前症状分别为背痛(29.2%)和主观下肢无力(75.5%)。所有 TDH 伴 PBA 均分布在下胸段,而 CDH 主要分布在中胸段和下胸段。TDH 伴 PBA 在男性中比 TDH 和 CDH 更常见。与 TDH、TDHO 和 TDH 伴 PVO 相比,TDH 伴 PBA 的手术年龄更年轻,TDH 和 CDH 的术前 JOA 评分低于 TDH 伴 PBA。与 TDH、TDHO 和 TDH 伴 PBA 相比,CDH 的腹侧占位比更大。
TDM 的发病通常隐匿,但可能因明显轻微的事件而急性发作。TDM 发病率低,临床表现多样。不同类型的 TDM 具有不同的临床特征,这可能表明不同的病理机制。