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特发性成人起病局灶性肌张力障碍的神经影像学。

Neuroimaging in idiopathic adult-onset focal dystonia.

机构信息

Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy.

IRCCS Neuromed, Pozzilli, Italy.

出版信息

Neurol Sci. 2021 Jul;42(7):2947-2950. doi: 10.1007/s10072-020-05025-w. Epub 2021 Jan 3.

Abstract

We aimed to study the attitude of Italian neurologists in the use of conventional MRI in patients with idiopathic adult-onset focal dystonia. Patients were included in the Italian Dystonia Registry by experts working in different Italian centers. MRI was available for 1045 of the 1471 (71%) patients included in the analysis. Using logistic regression analysis, we found that MRI was more likely to be performed in patients with cervical dystonia, spasmodic dysphonia, or non-task-specific upper limb dystonia, whereas it was less likely to be performed in patients with blepharospasm or task-specific upper limb dystonia. We did not find differences in the number of MRIs performed between neurological centers in Northern, Central, and Southern Italy. We conclude that although the diagnosis of idiopathic adult-onset dystonia is mainly based on clinical grounds, many movement disorder experts rely on MRI to confirm a diagnosis of idiopathic dystonia. We suggest that neuroimaging should be used in patients with adult-onset focal dystonia to rule out secondary forms.

摘要

我们旨在研究意大利神经病学家在使用常规 MRI 检查特发性成人起病局灶性肌张力障碍患者中的态度。患者由在不同意大利中心工作的专家纳入意大利肌张力障碍登记处。在纳入分析的 1471 名患者中的 1045 名患者中,MRI 可用。通过逻辑回归分析,我们发现 MRI 更有可能在患有颈肌张力障碍、痉挛性发音障碍或非任务特异性上肢肌张力障碍的患者中进行,而在患有眼睑痉挛或任务特异性上肢肌张力障碍的患者中则不太可能进行。我们没有发现意大利北部、中部和南部神经科中心之间进行的 MRI 数量存在差异。我们得出的结论是,尽管特发性成人起病肌张力障碍的诊断主要基于临床依据,但许多运动障碍专家依靠 MRI 来确认特发性肌张力障碍的诊断。我们建议在成年起病局灶性肌张力障碍患者中使用神经影像学检查以排除继发性疾病。

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