Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 833, Taiwan, ROC.
Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Ann Nucl Med. 2021 Feb;35(2):203-210. doi: 10.1007/s12149-020-01553-9. Epub 2021 Jan 3.
For Tc-sestamibi parathyroid single photon emission computed tomography/computed tomography (SPECT/CT), the traditional full-arc 360° acquisition technique has been suggested but not the theoretically low tissue-attenuated anterior 180° method. We aimed to compare the diagnostic performances and target-to-background ratios of anterior 180° and 360° SPECT/CT imaging.
Ninety-nine patients who underwent Tc-sestamibi scintigraphy and received a surgical-pathological diagnosis of parathyroid adenoma or hyperplasia were enrolled. The SPECT/CT reconstructed images with anterior 180° and full-arc 360° data were interpreted by two physicians using a scoring scale, and the lesions were semi-quantified using target-to-background ratios for both image sets.
In total, 113 abnormal parathyroid lesions were identified on the SPECT/CT images. The agreements of interpretation between the two image sets and readers were very good (κ value: 0.83-1.00). The accuracies of summative interpretation for the anterior 180° and full-arc 360° SPECT/CT were 83.04% and 82.46%, respectively. The target-to-background ratios were significantly higher for the anterior 180° than the full-arc 360° images (P < 0.01).
The anterior 180° SPECT/CT technique, a time-saving method, can provide satisfactory diagnostic performance and superior lesion contrast compared with the full-arc 360° SPECT/CT technique in Tc-sestamibi parathyroid imaging.
对于 Tc- sestamibi 甲状旁腺单光子发射计算机断层扫描/计算机断层扫描（SPECT/CT），传统的全弧 360°采集技术已经被提出，但不是理论上的低组织衰减的前 180°方法。我们旨在比较前 180°和 360° SPECT/CT 成像的诊断性能和靶/背景比。
纳入了 99 例接受 Tc-sestamibi 闪烁显像并接受甲状旁腺腺瘤或增生手术病理诊断的患者。使用评分标准由两位医师对前 180°和全弧 360°数据的 SPECT/CT 重建图像进行解读，并对两组图像的病灶进行半定量分析，以靶/背景比表示。
在 SPECT/CT 图像上共发现 113 个异常甲状旁腺病灶。两种图像集和两位读者之间的解读一致性非常好（κ 值：0.83-1.00）。前 180°和全弧 360° SPECT/CT 的综合解读准确率分别为 83.04%和 82.46%。前 180°的靶/背景比明显高于全弧 360°图像（P<0.01）。
在 Tc-sestamibi 甲状旁腺成像中，前 180° SPECT/CT 技术是一种节省时间的方法，与全弧 360° SPECT/CT 技术相比，它可以提供令人满意的诊断性能和更高的病灶对比度。
