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立体成像和数字三维模型评估皮肤科瘢痕:一项验证研究。

Dermatologic Scar Assessment With Stereoscopic Imaging and Digital Three-Dimensional Models: A Validation Study.

机构信息

Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Nielsine Nielsens Vej 17, Copenhagen NV, 2400, Denmark.

Cherry Imaging, Tavor Building 2, Yokneam, I.Z, 20692, Israel.

出版信息

Lasers Surg Med. 2021 Oct;53(8):1043-1049. doi: 10.1002/lsm.23373. Epub 2021 Jan 3.

Abstract

BACKGROUND AND OBJECTIVE

We evaluated a new handheld stereoscopic imaging system capable of visualizing scars with digital three-dimensional (3D) models and providing automated morphometric estimates. The objective was to validate the repeatability and accuracy of intra- and inter-investigator scan results.

STUDY DESIGN/MATERIALS AND METHODS: Engineered metal plates with depressed and elevated model scars (n = 72) were scanned six times by one investigator. In vivo hypertrophic and atrophic scars (n = 15) were scanned once by three investigators. The repeatability of morphometric estimates was assessed using coefficients of variation (CVs) to compare the variation among multiple scan results for both models and in vivo scars, with 0% reflecting a perfect match. Scar estimates from digital 3D reconstructions were compared with the known dimensions of physical model scars and with ruler measurements of in vivo scars.

RESULTS

A total of 48 model scars and 12 in vivo scars were eligible for automated analyses with the imaging system's proprietary software. Intra-investigator scan results for the model scars were repeatable, with low variance for all parameters: volume, area, length, and depth/height (CV: 1.8-3.1%). By comparison, inter-investigator scans of real in vivo scars resulted in slightly higher median CVs (4.4-7.3%; P < 0.05). 3D model scar estimates correlated well with the known physical dimensions of model scars for all parameters (P < 0.001) and accurately reflected the measurements of in vivo scars (P < 0.001). The six in vivo scars situated on the chest and abdomen showed the highest inter-investigator variation, due to respiratory movement artifacts.

CONCLUSION

Stereoscopic imaging of scars generates accurate and repeatable measurement estimates that show little intra- and inter-investigator-based assessment variation. The best results are achieved by minimizing subject movement. Lasers Surg. Med. © 2020 Wiley Periodicals LLC.

摘要

背景与目的

我们评估了一种新的手持式立体成像系统,该系统能够通过数字三维(3D)模型可视化疤痕,并提供自动形态计量估计。目的是验证同一观察者和不同观察者扫描结果的可重复性和准确性。

研究设计/材料和方法:对具有凹陷和凸起模型疤痕的工程金属板(n=72)由一位观察者进行了六次扫描。对三位观察者进行了一次 15 例增生性和萎缩性疤痕的活体扫描。使用变异系数(CV)评估形态计量估计的重复性,以比较模型和活体疤痕的多次扫描结果之间的差异,0%表示完全匹配。从数字 3D 重建中获得的疤痕估计值与物理模型疤痕的已知尺寸以及活体疤痕的标尺测量值进行了比较。

结果

共有 48 个模型疤痕和 12 个活体疤痕符合成像系统专有软件的自动分析条件。模型疤痕的观察者内扫描结果具有可重复性,所有参数的方差均较低:体积、面积、长度和深度/高度(CV:1.8-3.1%)。相比之下,真实活体疤痕的观察者间扫描结果产生的中位数 CV 略高(4.4-7.3%;P<0.05)。3D 模型疤痕估计与模型疤痕的已知物理尺寸高度相关(P<0.001),并准确反映了活体疤痕的测量值(P<0.001)。六个位于胸部和腹部的活体疤痕由于呼吸运动伪影导致观察者间差异最大。

结论

疤痕的立体成像可生成准确且可重复的测量估计值,并且基于观察者的评估变化很小。通过最小化受试者的运动,可以获得最佳结果。激光外科学和医学。© 2020 威利父子公司。

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