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2
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J Ophthalmol. 2016;2016:6980281. doi: 10.1155/2016/6980281. Epub 2016 Jun 5.
3
Clinical manifestations of sleep apnea.睡眠呼吸暂停的临床表现。
J Thorac Dis. 2015 Sep;7(9):E298-310. doi: 10.3978/j.issn.2072-1439.2015.09.13.
4
Deleterious systemic effects of OSA: how much evidence do we need?阻塞性睡眠呼吸暂停的有害全身影响:我们需要多少证据?
Thorax. 2015 Sep;70(9):817-8. doi: 10.1136/thoraxjnl-2015-207247. Epub 2015 Jul 14.
5
The floppy eyelid syndrome: evaluating lid laxity and its correlation to sleep apnea syndrome and body mass index.眼睑松弛综合征:评估眼睑松弛及其与睡眠呼吸暂停综合征和体重指数的相关性。
ISRN Ophthalmol. 2012 Jun 20;2012:650892. doi: 10.5402/2012/650892. eCollection 2012.
6
Does this patient have obstructive sleep apnea?: The Rational Clinical Examination systematic review.这位患者是否患有阻塞性睡眠呼吸暂停?:理性临床检查系统评价。
JAMA. 2013 Aug 21;310(7):731-41. doi: 10.1001/jama.2013.276185.
7
Increased prevalence of sleep-disordered breathing in adults.成年人睡眠呼吸紊乱患病率增加。
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8
The relationship between floppy eyelid syndrome and obstructive sleep apnoea.眼睑松弛综合征与阻塞性睡眠呼吸暂停的关系。
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Floppy eyelid syndrome is associated with obstructive sleep apnoea: a prospective study on 127 patients.眼睑松弛综合征与阻塞性睡眠呼吸暂停相关:127 例患者的前瞻性研究。
J Sleep Res. 2012 Jun;21(3):308-15. doi: 10.1111/j.1365-2869.2011.00968.x. Epub 2011 Oct 11.
10
Obstructive sleep apnea among patients with retinal vein occlusion.视网膜静脉阻塞患者中的阻塞性睡眠呼吸暂停
Arch Ophthalmol. 2010 Dec;128(12):1533-8. doi: 10.1001/archophthalmol.2010.272.

评估阻塞性睡眠呼吸暂停综合征的眶周组织。

Evaluation of Periorbital Tissues in Obstructive Sleep Apnea Syndrome.

机构信息

Ege University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey.

Ege University Faculty of Medicine, Department of Chest Diseases, İzmir, Turkey.

出版信息

Turk J Ophthalmol. 2020 Dec 29;50(6):356-361. doi: 10.4274/tjo.galenos.2020.35033.

DOI:10.4274/tjo.galenos.2020.35033
PMID:33389936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7802102/
Abstract

OBJECTIVES

To evaluate periorbital tissue alterations including eyelid laxity and eyelash ptosis in patients with obstructive sleep apnea syndrome (OSAS).

MATERIALS AND METHODS

Based on polysomnography, 96 eyes of 48 patients with moderate/severe OSAS (Group 1) and 44 eyes of 22 patients with simple snoring (Group 2) were enrolled. Comprehensive eye examination along with eyelid laxity measurements including vertical and anterior distraction, presence of dermatochalasis, interpalpebral distance, and levator function were assessed. The presence and severity of eyelash ptosis were also noted.

RESULTS

The mean ages of Group 1 and Group 2 were 49.9±11.4 (range: 26-67) and 50.6±8.9 (range: 27-69) years, respectively (p=0.557). The mean vertical and anterior distraction distances in Group 1 (13.3±4.1 [range, 6-27] mm and 7.4±2.1 [range, 3-13.5] mm, respectively) were significantly higher than in Group 2 (p<0.05). Dermatochalasis and eyelash ptosis were found to be significantly more frequent in Group 1 (52.1% and 81.3%, respectively). The severity of eyelash ptosis was also higher in OSAS (p<0.05). No significant difference in interpalpebral distance or levator muscle function was detected.

CONCLUSION

In patients with severe OSAS, eyelid laxity was more prominent and eyelash ptosis was more frequent and severe.

摘要

目的

评估阻塞性睡眠呼吸暂停综合征(OSAS)患者的眶周组织改变,包括眼睑松弛和睫毛下垂。

材料和方法

根据多导睡眠图,纳入 48 例中重度 OSAS 患者(1 组)的 96 只眼和 22 例单纯打鼾患者(2 组)的 44 只眼。评估全面的眼部检查以及眼睑松弛度测量,包括垂直和前向分离、皮肤松弛、睑裂宽度和提上睑肌功能。还记录了睫毛下垂的存在和严重程度。

结果

1 组和 2 组的平均年龄分别为 49.9±11.4(范围:26-67)和 50.6±8.9(范围:27-69)岁(p=0.557)。1 组的平均垂直和前向分离距离(13.3±4.1 [范围:6-27] mm 和 7.4±2.1 [范围:3-13.5] mm)显著高于 2 组(p<0.05)。1 组的皮肤松弛和睫毛下垂的发生率明显更高(分别为 52.1%和 81.3%)。OSAS 患者的睫毛下垂严重程度也更高(p<0.05)。未检测到睑裂宽度或提上睑肌功能的显著差异。

结论

在重度 OSAS 患者中,眼睑松弛更为明显,睫毛下垂更为频繁和严重。