Matsugasumi Toru, Nakanishi Hiroyuki, Yokota Tomohiro, Shiraishi Takumi, Ukimura Osamu
Department of Urology Kyoto Chubu Medical Center Nantan City Kyoto Japan.
Department of Urology Kyoto Prefectural University of Medicine Kyoto Japan.
IJU Case Rep. 2020 Apr 20;3(4):121-124. doi: 10.1002/iju5.12161. eCollection 2020 Jul.
Secondary bladder, colon, and rectal cancers are relatively common after prostate radiotherapy. However, secondary squamous cell carcinoma of the prostate is rare.
An 85-year-old man presented with dysuria and low-serum prostate-specific antigen levels. His medical history included localized prostate adenocarcinoma (Gleason score of 4 + 5) treated with combined three-dimensional conformal radiotherapy and androgen deprivation therapy, 11 years ago. Urethroscopy and magnetic resonance imaging showed a bulging mass around the prostatic urethra. Transurethral resection of the prostate performed for histopathological diagnosis revealed squamous cell carcinoma.
Hereby, a rare case of secondary squamous cell carcinoma of the prostate after radiotherapy for adenocarcinoma was reported, which was found after 11 years of radiotherapy with symptom of dysuria including urinary hesitancy, difficulty, pain during urination, and low-serum prostate-specific antigen levels.
前列腺放疗后，继发性膀胱癌、结肠癌和直肠癌相对常见。然而，继发性前列腺鳞状细胞癌却很罕见。
一名85岁男性出现排尿困难且血清前列腺特异性抗原水平较低。他的病史包括11年前接受三维适形放疗和雄激素剥夺治疗的局限性前列腺腺癌（ Gleason评分4 + 5）。尿道镜检查和磁共振成像显示前列腺尿道周围有一个隆起的肿块。经尿道前列腺切除术进行组织病理学诊断显示为鳞状细胞癌。
在此，报告了一例腺癌放疗后罕见的继发性前列腺鳞状细胞癌病例，该病例在放疗11年后出现，伴有排尿困难症状，包括排尿犹豫、困难、尿痛，以及血清前列腺特异性抗原水平较低。
