Department of Endodontics, Faculty of Dentistry, Ondokuz Mayis University, 55200, Samsun, Turkey.
Ordu Oral and Dental Health Center, Ordu, Turkey.
Clin Oral Investig. 2021 Jul;25(7):4407-4413. doi: 10.1007/s00784-020-03753-z. Epub 2021 Jan 3.
This study evaluated the efficacy of 5% and 10% glycolic acid solutions for the removal of calcium hydroxide medicament from artificial internal resorption cavities.
A total of 170 human maxillary premolars were selected and artificial internal resorption cavities were prepared using round burs and 37% orthophosphoric acid in the apical third of the root halves. Entire canal and resorption cavity were filled with calcium hydroxide paste. Then, the specimens were assigned to 2 control groups or ten experimental groups according to the irrigating solutions used for medicament removal with and without activation with ultrasonic energy as following: 5% glycolic acid, 10% glycolic acid, 17% EDTA, and 10% citric acid and distilled water. The resorption cavities were examined under different magnifications using stereomicroscopy and scanning electron microscopy (SEM). The calcium hydroxide remnants in the resorption cavity were scored by 2 evaluators using a 4-scoring scale. The data were analyzed with Kruskal-Wallis H tests with 5% significance threshold.
There was no significant difference regarding the distribution of removal scores among non-activated solutions (P > 0.05). In activated groups, 10% glycolic acid irrigation removed significantly more amount of calcium hydroxide than EDTA and distilled water (P < 0.05). No significant difference was found between the efficacy of 10% glycolic and citric acid (P > 0.05). Citric acid, 5% glycolic acid, and EDTA showed similar removal scores (P > 0.05). Passive ultrasonic irrigation significantly improved calcium hydroxide removal scores in 10% glycolic acid, citric acid, and EDTA groups (P < 0.05). The SEM examination revealed that the specimens that were scored 0 are not entirely free of calcium hydroxide remnants.
Concentration of 10% glycolic acid removed significantly more calcium hydroxide paste from resorption cavities than EDTA when used with passive ultrasonic irrigation. Although passive ultrasonic irrigation favored medicament removal in all irrigating solutions, complete elimination of medicament remnants was unattainable.
This study showed the improved efficacy of ultrasonically activated 10% glycolic acid in removing the calcium hydroxide medicament from the internal resorption cavity.
本研究评估了 5%和 10%的甘醇酸溶液在去除人工内吸收腔中的氢氧化钙药物方面的疗效。
共选择 170 个人上颌前磨牙，使用根管锉和 37%磷酸在根尖三分之一处制备人工内吸收腔。整个根管和吸收腔都填充了氢氧化钙糊剂。然后，根据是否使用超声能量激活，将标本分为 2 个对照组或 10 个实验组，实验组的冲洗液分别为 5%甘醇酸、10%甘醇酸、17%EDTA 和 10%柠檬酸及蒸馏水。使用立体显微镜和扫描电子显微镜（SEM）在不同放大倍数下检查吸收腔。两名评估员使用 4 分制评分标准对吸收腔中的氢氧化钙残余物进行评分。数据采用 Kruskal-Wallis H 检验，显著性水平为 5%。
非激活溶液组之间的去除评分分布无显著差异（P＞0.05）。在激活组中，10%甘醇酸冲洗液去除的氢氧化钙量明显多于 EDTA 和蒸馏水（P＜0.05）。10%甘醇酸和柠檬酸的疗效无显著差异（P＞0.05）。柠檬酸、5%甘醇酸和 EDTA 的去除评分相似（P＞0.05）。被动超声冲洗显著提高了 10%甘醇酸、柠檬酸和 EDTA 组的氢氧化钙去除评分（P＜0.05）。SEM 检查显示，评分 0 的标本并非完全不含氢氧化钙残余物。
在使用被动超声冲洗时，浓度为 10%的甘醇酸从吸收腔中去除的氢氧化钙糊剂明显多于 EDTA。尽管被动超声冲洗有利于所有冲洗液中的药物去除，但药物残余物的完全清除是无法实现的。
本研究显示，超声激活的 10%甘醇酸在从内吸收腔中去除氢氧化钙药物方面的疗效有所提高。
