Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education)/Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Environ Sci Technol. 2021 Jan 19;55(2):1122-1133. doi: 10.1021/acs.est.0c05048. Epub 2021 Jan 4.
Engineered nanomaterials (ENMs), especially transition metal dichalcogenide (TMDC), have received great attention in recent years due to their advantageous properties and applications in various fields and are inevitably released into the environment during their life cycle. However, the effect of natural nanocolloids, widely distributed in the aquatic environment, on the environmental transformation and ecotoxicity of ENMs remains largely unknown. In this study, the effects of natural nanocolloids were compared to humic acid on the environmental transformation and ecotoxicity of single-layer molybdenum disulfide (SLMoS), a representative TMDC. SLMoS with nanocolloids or humic acid (HA) enhanced their dispersion and Mo ion release in deionized water. Nanocolloids induced growth inhibition, reactive oxygen species (ROS) elevation, and cell permeability. Low-toxicity SLMoS combined with nanocolloids will enhance the above adverse effects. SLMoS-nanocolloids induced serious damage (cell distortion and deformation), SLMoS internalization, and metabolic perturbation on (). In contrast, the addition of HA induced the growth promotion and lower ROS level, inhibited the internalization of SLMoS, and mitigated metabolic perturbation on . This work provides insights into the effect of natural nanocolloids on the behaviors and biological risks of ENMs in aquatic environments, deserving substantial future attention.
近年来，由于具有优越的性能和在各个领域的广泛应用，工程纳米材料（ENMs），特别是过渡金属二硫属化物（TMDC），受到了极大的关注。然而，在其生命周期中不可避免地会释放到环境中，广泛分布在水生环境中的天然纳米胶体对 ENMs 的环境转化和生态毒性的影响在很大程度上仍然未知。在这项研究中，比较了天然纳米胶体和腐殖酸（HA）对单层二硫化钼（SLMoS），一种典型的 TMDC 的环境转化和生态毒性的影响。在去离子水中，带纳米胶体或腐殖酸（HA）的 SLMoS 增强了其分散性和 Mo 离子释放。纳米胶体诱导生长抑制、活性氧（ROS）升高和细胞通透性。低毒性的 SLMoS 与纳米胶体结合会增强上述不良影响。SLMoS-纳米胶体对 （）诱导严重损伤（细胞变形和变形）、SLMoS 内化和代谢扰动。相比之下，HA 的添加诱导了生长促进和较低的 ROS 水平，抑制了 SLMoS 的内化，并减轻了对 的代谢扰动。这项工作深入了解了天然纳米胶体对水生环境中 ENMs 行为和生物风险的影响，值得未来进一步关注。
