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整体肺指数在呼吸困难患者中肺栓塞的应用性能。

Performance of integrated pulmonary index for pulmonary embolism in dyspneic patients.

出版信息

Bratisl Lek Listy. 2021;122(1):65-70. doi: 10.4149/BLL_2021_008.

DOI:10.4149/BLL_2021_008
PMID:33393323
Abstract

OBJECTIVES

The aim of this study was to evaluate the diagnostic capacity of integrated pulmonary index (IPI) in predicting the pulmonary embolism (PE) in patients admitted to emergency departments (ED) with dyspnea.

BACKGROUND

The acute dyspnea is one of the most common chief complaints in EDs. PE is a potentially fatal disease and the delay in specific therapy increases the worst outcomes.

METHODS

This study is a prospective methodological study, in which we evaluated the diagnostic performance of the IPI in predicting PE in patients admitted to ED with dyspnea. ROC analysis was used for estimating the accuracy of IPI and OCRS.

RESULTS

Of the 144 patients included in the study, there were 20 (13.9 %) PE patients. In the ROC analysis, the best cut-off point for IPI was ≤ 2. For this cut-off point, the sensitivity and specificity of IPI were 100.0 % and 96.0 %, respectively. Besides, the accuracy of IPI was 96.5 % with a +LR of 24.8 and a -LR of 0.0.

CONCLUSION

IPI was a potential candidate for evaluating the respiratory status, and a limiting tool to prevent unnecessary diagnostic tests and save time in determining the treatment course in dyspneic patients at ED (Tab. 5, Fig. 3, Ref. 34).

摘要

目的

本研究旨在评估综合肺部指数(IPI)在预测因呼吸困难而就诊于急诊科(ED)的患者中肺栓塞(PE)的诊断能力。

背景

急性呼吸困难是 ED 中最常见的主诉之一。PE 是一种潜在的致命疾病,特定治疗的延迟会增加最坏的结果。

方法

这是一项前瞻性方法学研究,我们评估了 IPI 在预测因呼吸困难而就诊于 ED 的患者中 PE 的诊断性能。ROC 分析用于估计 IPI 和 OCRS 的准确性。

结果

在纳入研究的 144 名患者中,有 20 名(13.9%)PE 患者。在 ROC 分析中,IPI ≤ 2 的最佳截断点。对于该截断点,IPI 的敏感性和特异性分别为 100.0%和 96.0%。此外,IPI 的准确性为 96.5%,阳性似然比为 24.8,阴性似然比为 0.0。

结论

IPI 是评估呼吸状态的潜在候选指标,也是一种限制工具,可以防止在 ED 呼吸困难患者中进行不必要的诊断性检查,并在确定治疗过程方面节省时间(表 5,图 3,参考文献 34)。

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