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氯胺酮治疗复杂性区域疼痛综合征(CRPS)患者的麻醉管理。

Anesthetic Management of a Complex Regional Pain Syndrome (CRPS) Patient With Ketamine.

机构信息

Resident in Orofacial Pain and Oral Medicine, The Herman Ostrow School of Dentistry at the University of Southern California, Los Angeles, California.

Director, Dental Anesthesiology Residency Program, Jacobi Medical Center Bronx, New York.

出版信息

Anesth Prog. 2020 Dec 1;67(4):219-225. doi: 10.2344/anpr-67-02-07.

Abstract

Complex regional pain syndrome (CRPS) is a potentially debilitating form of neuropathic pain that may manifest following a traumatic injury or surgery. CRPS is also known as algodystrophy, causalgia, or reflex sympathetic dystrophy (RSD). Patients describe unbearable burning pain from nonnociceptive stimuli, such as when taking a shower or brushing against another object. Regular tactile stimuli encountered during routine dental procedures may not be well-tolerated by a patient with CRPS. Ketamine infusions have been reported to help alleviate acute exacerbations or "flare-ups" of CRPS symptoms. This case report provides a brief overview of CRPS pathophysiology and treatment including data supporting the use of ketamine infusions and a discussion regarding the anesthetic management of a patient with CRPS presenting for dental care under deep sedation utilizing high-dose intravenous ketamine.

摘要

复杂性区域疼痛综合征(CRPS)是一种潜在的使人衰弱的神经性疼痛,可能在创伤或手术后出现。CRPS 也被称为反射性交感神经营养不良症、灼痛症或反射性交感神经营养不良症(RSD)。患者会描述出难以忍受的烧灼感,来自非伤害性刺激,例如洗澡或碰到其他物体。经常在常规牙科手术中遇到的常规触觉刺激,可能会被患有 CRPS 的患者难以忍受。据报道,氯胺酮输注有助于缓解 CRPS 症状的急性加重或“发作”。本病例报告简要概述了 CRPS 的病理生理学和治疗方法,包括支持使用氯胺酮输注的数据,并讨论了在深度镇静下使用大剂量静脉注射氯胺酮进行牙科护理的 CRPS 患者的麻醉管理。

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